Morphological study of rats kidneys after the simulation of rhabdomyolytic acute kidney injury by the single injection of 50% glycerol revealed the morphological changes in the renal cortex and medulla, which were manifested by the luminal obstruction of the cortical and medullary tubules with myoglobin casts, epithelial dystrophy and signs of coagulative necrosis. Use of glutathione improved t...

Phytochemical study of the aerial parts of Ficus palmata utilizing liquid-liquid fractionation and different chromatographic techniques resulted in the isolation of a new isomer of psoralenoside namely, trans-psoralenoside (5) in addition to, one triterpene: germanicol acetate (1), two furanocoumarins: psoralene (2), bergapten (3), one aromatic acid vanillic acid (4) and the flavone glycoside r...

Medicinal plants may serve as a vital source of potentially useful new compounds for the development of effective therapy to combat a variety of kidney problems. Many herbs have been proven to be effectual as nephroprotective agents while many more are claimed to be nephroprotective but there is lack of any such scientific evidence to support such claims. Developing a satisfactory herbal therap...

Aim: The aim of the present investigation is to study nephroprotective activity two indigenous medicinal plants. Material and methods: Dried leaves Alstonia scholaris Centella asiatica were procured from garden campus Pharmacy College in month September, Bhopal, Madhya Pradesh, India. Around 500 gm dried coarsely powdered weighed filled Soxhlet apparatus for extraction. Wistar albino rats eithe...

Kidney diseases are a major problem of worldwide proportions and renal damage is very common since kidney has the capacity to excrete toxic substances. A phytotherapeutic approach to modern drug development can provide many invaluable drugs from traditional medicinal plants. Search for pure photochemical as drugs is time consuming and expensive. Numerous plants and polyherbal formulations are u...

hydroalcoholic extract (70% ethanol extract) of tubers of momordica tuberosa cogn. (cucurbitaceae) was subjected to preliminary phytochemical screening by qualitative tests. nitric oxide scavenging activity was performed by griess reagent method. and nephroprotective activity was assessed in gentamicin, cisplatin and paracetamol induced renal damage in wistar rats (150-200 g) by standard method...

Green tea and hibiscus are widely consumed as traditional beverages in Yemen and some regional countries. They are relatively cheap and the belief is that they improve health state and cure many diseases. The aim of this study was to evaluate the potential protective and antibacterial activity of these two famous plants in vitro through measuring their antibacterial activity and in vivo through...