purpose : to compare the ability of scanning laser polarimetry (gdx vcc), and optical coherence tomography (oct) to discriminate eyes with primary open angle glaucoma (poag) from normal eyes and to assess the relationship between their parameters methods : eighty-seven glaucomatous eyes of 87 patients and 25 normal eyes were enrolled. the mean age of patients and normal group were 54.96±18.34 a...

The relationship of the vasculature to the neuronal layers was studied in whole-mounts and in sections of macaque retinas. Like other central nervous structures, primate retinas have local variations in vascularity that reflect local variations in metabolism, rather than simply tissue thickness or volume. A special feature of the retina is a dense vascular plexus in the nerve fiber layer, which...

purpose: to determine peripapillary retinal nerve fiber layer (rnfl) thickness by three-dimensional optical coherence tomography (3d-oct) in a normal iranian population and to evaluate the concordance of these measurements with those obtained by the second generation of optical coherence tomography (oct ii). methods: in a cross-sectional observational study, 96 normal iranian subjects 20-53 yea...

PURPOSE To determine the effects of X-linked and autosomal recessive Alport syndrome on retinal basement membranes and how these result in the characteristic perimacular dot-and-fleck retinopathy, lozenge, and macular hole. METHODS The type IV collagen chains present in the normal retina were determined immunohistochemically. Ten patients with Alport syndrome underwent retinal photography and...

PURPOSES To evaluate the retinal nerve fiber layer using GDx in chronic alcohol and tobacco users. METHODS Twenty-three chronic alcohol and tobacco users were studied (study group). As a control group, sixteen volunteers without use of alcohol and tobacco with similar characteristics (age, gender and race) were included. Both eyes were tested for analysis of the retinal nerve fiber layer with...

multiple sclerosis (ms) is the most prevalent disease caused by the inflammatory demyelinating process that causes progressive nervous system degeneration over the time. optical coherence tomography (oct) is a non-invasive optical imaging technology, which can measure the thickness of retinal nerve fiber layer as well as the diameter of the macula. the purpose of the study is evaluation oct fin...

PURPOSES To evaluate the retina nerve fiber layer by laser polarimetry in patients in chronic use of chloroquine. METHODS Forty-four eyes of twenty-two patients were studied. These were in use of chloroquine due to rheumatic diseases during at least one year. As a control group, twenty patients without use of chloroquine with similar characteristics (age, gender and race) were included. Patie...

PURPOSE To compare the optical coherence tomography retinal nerve fiber layer and macular thickness measurements for detection of progressive axonal loss following acute traumatic optic neuropathy in a longitudinal study. METHODS Three patients with unilateral traumatic optic neuropathy were evaluated sequentially after trauma. Macular and retinal nerve fiber layer thickness measurements were...

Early attrition of nerve fiber bundles in glaucoma causes slit-like gaps to appear among the normally uniform, striated arcuate bundles of the retinal nerve fiber layer. The nerve fiber layer thins progressively, and its vessels become exposed as the defects coalesce, deepen, and widen with advancing disease. These changes in the peripapillary retina are exemplified photographically and compare...

The neural capacity (NC) of high-pass resolution perimetry (HRP) was compared to the retinal nerve fiber layer thickness measured with the GDx Nerve Fiber Analyzer in 74 patients with either ocular hypertension or primary open-angle glaucoma at various stages of severity. A statistically significant correlation was found between the NC and the GDx ellipse average, the total polar integral, and ...