BACKGROUND To find the correlations and differences between the nerve fiber layer parameters of a GDx (polarimetric retinal nerve fiber analyzer) in single high quality images and those in the mean image from three high quality images. METHODS The results of scanning laser polarimetry were selected from 63 eyes of 63 patients (31 male and 32 female). Complete ophthalmic examinations included ...

OBJECTIVE To assess the relationship between in vivo measurements of optic disc topography and histomorphometric measurements of optic nerve fiber number in glaucoma. METHODS Both eyes of 10 monkeys (Macaca fascicularis) with laser-induced glaucoma in the right eye were studied. Optic disc topography was measured in vivo with a confocal scanning laser ophthalmoscope. Histomorphometry was perf...

OBJECTIVE To assess optical coherence tomography in differentiating optic disc edema (ODE) due to papilledema and other optic neuropathies from optic nerve head drusen (ONHD). METHODS Optical coherence tomographic images from 60 subjects (20 with ODE, 20 with ONHD, and 20 control subjects) were assessed qualitatively and quantitatively. Qualitative criteria for ODE included an elevated optic ...

Introduction: Prior qualitative and quantitative studies have reported morphological changes that occur in nerve fibers and non-neuronal cells of peripheral nerve during the lifetime of the rats. Previous studies suggest that Aloe Vera has some beneficial and therapeutic effects such as anti-oxidant effects. In the current study, we have evaluated histological and histomorphometric changes of Sc...

The relationship of the vasculature to the neuronal layers was studied in whole-mounts and in sections of macaque retinas. Like other central nervous structures, primate retinas have local variations in vascularity that reflect local variations in metabolism, rather than simply tissue thickness or volume. A special feature of the retina is a dense vascular plexus in the nerve fiber layer, which...

Purpose. To evaluate the relationship between the macular ganglion cell complex (mGCC) thickness, which is the sum of the retinal nerve fiber, ganglion cell, and inner plexiform layers, measured with a spectral-domain optical coherence tomograph and the optic nerve head topography measured with a confocal scanning laser ophthalmoscope in glaucomatous eyes with visual field defects localized pre...

PURPOSE This study was designed to assess and compare the thicknesses of the fovea and the retinal nerve fiber layer in normal children and children with amblyopia. METHODS Optical Coherence Tomography (OCT) was performed on 26 children (52 eyes total) with unilateral amblyopia that was due to anisometropia or strabismus. OCT was also performed on 42 normal children (84 eyes), for a total of ...

The neural capacity (NC) of high-pass resolution perimetry (HRP) was compared to the retinal nerve fiber layer thickness measured with the GDx Nerve Fiber Analyzer in 74 patients with either ocular hypertension or primary open-angle glaucoma at various stages of severity. A statistically significant correlation was found between the NC and the GDx ellipse average, the total polar integral, and ...

BACKGROUND Peripheral nerve repair is often complicated by fibroblastic scar formation, nerve dysfunction, and traumatic neuroma formation. Use of silicone may improve outcomes of these repairs. In this study, we tried to evaluate effectiveness of silicone gel on rats’ sciatic nerve repair, axon regeneration and scar formation around and in the nervous tissues. METHODS This experimental stud...