This paper deals with the role of widespread neuro-immuno-endocrine-endothelial system in sport traumatology. The aim this work is to see if or regular physical activity able reprogram endothelium, advance new concept diffused system, and introduce practice medicine a test fields “Athlete functional evaluation” “Sports fitness”. first object whether can change structure endothelium. second goal...

Primary large-cell neuro-endocrine carcinoma of the bladder is a rare aggressive tumour with a very poor prognosis. The authors report the case of 78-year-old male patient with primary large-cell neuro-endocrine carcinoma of the bladder and discuss the pathological and therapeutic aspects of this tumour in the light of a review of the literature.

Neuroendocrine tumours constitute a group of tumours that originate from neuroendocrine cells throughout the body. That includes endocrine tumours of the thymus, lung, pancreas and gastrointestinal tract. Neuroendocrine gastrointestinal tumours have classically been divided into carcinoid tumours and endocrine pancreatic tumours. Many of these tumours produce hormones that can induce clinical s...

scientific evidence regarding the efficacy and safety of the ldm approach in the treatment of psoriasis vulgaris, and positive preliminary data regarding the oral administration of low dose activated cytokines for vitiligo and atopic dermatitis treatment, support the ldm-based therapeutic approach for many dermatological diseases. ldm suggests the use of low-doses of activated biological molecu...

Aims: In order to clarify the role of β-catenin in digestive endocrine carcinogenesis, we analyzed a large and representative series of gastroenteropancreatic endocrine tumours in order to determine the incidence and pattern of β−catenin alterations and to analyze the clinical, and histological characteristics of the tumours presenting immunohistochemically detectable alterations in β−catenin e...

Neuroendocrine tumours belong to a heterogeneous family of neoplasms, originating in endocrine glands (such as the pituitary, parathyroid or the neuroendocrine adrenal glands), in endocrine islets (within the thyroid or pancreas) as well as in endocrine cells dispersed between exocrine cells throughout the digestive or respiratory tracts. The clinical behaviour of neuroendocrine tumours is vari...

Abstract A paraganglioma of the bladder is a rare condition. Paraganglioma may case general symptoms illness like sweating or headache. When performing transurethral resection paraganglioma, an antiadrenergic intervention advised since can trigger hypertensive crisis. 65-year-old female was under surveillance after radical nephroureterectomy because pTaG2 urothelial carcinoma renal pelvis. year...

We present an overview of the role of neuro-endocrine-immune mechanisms in the pathophysiological responses of patients with rheumatoid arthritis (RA). In patients with RA, proinflammatory cytokines secreted by synovial cells provoke local inflammation in the joints and, simultaneously, initiate a systemic acute phase response. Thus, profound changes of the neuro-endocrine-immune axis could tak...