the proportion of elderly in the general population is rising, resulting in greater numbers of drivers with neurodegenerative disorders such as alzheimer’s disease (ad) and parkinson’s disease (pd). alzheimer’s disease is a progressive neurodegenerative disorder typified by memory impairment with executive dysfunction, motor problems, and/or language difficulties. parkinson’s disease is a progr...

apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. it is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal dna fragmentation. although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...

abstract        background and objective: peroxidases catalyze protein oxidation and lipid peroxidation. the activity of these enzymes in nerve cells is involved in causing disorders such as alzheimer's and parkinson's disease. this study investigated the effect of citrus aurantium, foeniculum vulgare and rosmarinus officinalis essential oils on activity of peroxidase enzyme.       me...

endocannabinoid (ecb) system plays a vital role in responses to stress. moreover, ecb and its receptors cause anti-inflammatory, anti-oxidative and neuroprotective effects by modulating neuronal, glial and endothelial cell functions. a number of studies have demonstrated ecb system notably defects in neurotraumatic and neurodegenerative diseases like epilepsy, tbi, alzheimer’s disease and parki...

parkinson’s disease (pd) is the second most common neurodegenerative brain disorder which is around 1.5 times more common in men than in women. currently, drug medications, surgery, and lifestyle changes are common approaches to pd, while all of them focused on reducing the symptoms. therefore, regenerative medicine based on stem cell (sc) therapies has raised a promising hope. various types of...