نتایج جستجو برای: neuronal calcium sensor

تعداد نتایج: 465421  

Journal: :Neuron 2012
Qian Chen Joseph Cichon Wenting Wang Li Qiu Seok-Jin R. Lee Nolan R. Campbell Nicholas DeStefino Michael J. Goard Zhanyan Fu Ryohei Yasuda Loren L. Looger Benjamin R. Arenkiel Wen-Biao Gan Guoping Feng

The ability to chronically monitor neuronal activity in the living brain is essential for understanding the organization and function of the nervous system. The genetically encoded green fluorescent protein-based calcium sensor GCaMP provides a powerful tool for detecting calcium transients in neuronal somata, processes, and synapses that are triggered by neuronal activities. Here we report the...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Pétur O Heidarsson Mohsin M Naqvi Mariela R Otazo Alessandro Mossa Birthe B Kragelund Ciro Cecconi

Neurodegenerative disorders are strongly linked to protein misfolding, and crucial to their explication is a detailed understanding of the underlying structural rearrangements and pathways that govern the formation of misfolded states. Here we use single-molecule optical tweezers to monitor misfolding reactions of the human neuronal calcium sensor-1, a multispecific EF-hand protein involved in ...

2011
Mirza Muhammad Yasir Masood Mirza M Yasir Masood Noor M Khan

Efficient utilization of Energy is a hot topic of research in the field of wireless sensor networks (WSNs). Limited battery resource at a sensor node coupled with the hostile multi-path fading propagation environment makes the task of the network to provide reliable data services with an enhanced lifetime, challenging. In order to achieve this goal, a number of efforts have been made by the res...

Journal: :Biophysical Journal 2021

Downstream regulatory element antagonist modulator (DREAM) is a member of the neuronal calcium sensors family and expressed in hippocampus. DREAM involved memory, learning, pain sensitivity, kinetics potassium channels, homeostasis, gene expression enzymatic activity presenilin. It has also been linked to pathologies such as Parkinson Alzheimer's disease. The multifunctionality this protein due...

Journal: :Biochimica et Biophysica Acta (BBA) - General Subjects 2012

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