نتایج جستجو برای: neuronal damage
تعداد نتایج: 338450 فیلتر نتایج به سال:
objective(s): scutellarin, a flavonoid extracted from the medicinal herb erigeron breviscapus hand-mazz, protects neurons from damage and inhibits glial activation. here we examined whether scutellarin may also protect neurons from hypoxia-induced damage. materials and methods: mice were exposed to hypoxia for 7 days and then administered scutellarin (50 mg/kg/d) or vehicle for 30 days cognitiv...
BACKGROUND The effect of nitrous oxide on ischemic neuronal damage was quantitatively evaluated by use of logistic regression curves. METHODS Seventy-two gerbils were anesthetized with 1% halothane and randomly assigned to receive 70% nitrous oxide or 70% nitrogen. Forebrain ischemia was performed for 3, 5, or 7 min, and direct-current potential in the hippocampal CA1 region was recorded. His...
In contrast to traditional textbook paradigms, recent studies indicate neuronal damage in classic neuroinflammatory diseases of the brain, such as multiple sclerosis or meningitis. In these cases, immune cells invade the central nervous system compartments, accompanied by a massive breakdown of the blood-brain barrier and typical changes of the cerebrospinal fluid. On the other hand, inflammati...
Alzheimer's disease (AD) is a complex neurodegenerative disorder with a progressive template leading to neural damage as well as cognitive and memory deficit. The present study designed to investigate the neuroprotective effects of Centella Asiatica (CA) in STZ-induced rat model of memory impairment and neuronal damage. ICV infusion of STZ (3 mg/kg) or saline (as vehicle) were performed on days...
Introduction: In Iran, thousands of young individuals become victims of head injury annually. Head injury can damage neuronal cells which may in turn complicate the recovery of the patients. Also, the increase of iron in cerebrospinal fluid (CSF) following head injury may contribute to the hypoxic-ischemia brain damage by catalyzing the formation of free radicals (Harber-Weiss Rection). The obj...
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