The Neurotrauma Evidence Translation (NET) program was funded in 2009 to increase the uptake of research evidence in the clinical care of patients who have sustained traumatic brain injury. This paper reports the rationale and plan for this five-year knowledge translation research program. The overarching aims of the program are threefold: to improve outcomes for people with traumatic brain inj...

Abstract Introduction Introduction: Rapid eye movement (REM) sleep behavior disorder (RBD) is strongly associated with progressive phenoconversion to an overt synucleinopathy (e.g., parkinsonism). Neurotrauma [i.e., traumatic brain injury (TBI) and posttraumatic stress (PTSD)], increases the odds of RBD diagnosis by ~2.5-fold increased later Parkinson’s Disease (PD), a service-connected illness...

The adaptability of the central nervous system has been revealed in several model systems. Of particular interest to system-injured individuals is ability for neural components be modified regain function. In both types neurotrauma, traumatic brain injury and spinal cord injury, primary parasympathetic control gastrointestinal tract, vagus nerve, remains anatomically intact. However, with or ar...

Since time immemorial, neurotrauma has been recorded in various continents. The advancement in neurotraumatology ever since Denny Brown and Trussell’s landmark experimental study of concussion, has come a long way with major contributions from neuropathology, neurophysiology, neurochemistry, biomedical sciences, public policies, intensive care medicine and last but not the least, genetics. A si...

The frequency of and outcome from acute traumatic brain injury (TBI) in humans are detailed together with a classification of the principal focal and diffuse pathologies, and their mechanisms in extract laboratory models are outlined. Particular emphasis is given to diffuse axonal injury, which is a major determinant of outcome. Cellular and molecular cascades triggered by injury are described ...

s from The 34 Annual National Neurotrauma Symposium June 26–29, 2016 Lexington, Kentucky JOURNAL OF NEUROTRAUMA 33:A-1–A-139 (July 1, 2016) a Mary Ann Liebert, Inc. DOI: 10.1089/neu.2016.29008.abstracts D ow nl oa de d by N IH N A T IO N A L I N ST IT U T E S O F H E A L T H L IB R A R Y P A C K A G E f ro m o nl in e. lie be rt pu b. co m a t 0 2/ 14 /1 8. F or p er so na l u se o nl y.

Explosive blast traumatic brain injury (TBI) is one of the more serious wounds suffered by United States service members injured in the current conflicts in Iraq and Afghanistan. Some military medical treatments for blast TBI that have been introduced successfully in the war theater include decompressive craniectomy, cerebral angiography, transcranial Doppler, hypertonic resuscitation fluids, a...