A 70-year-old man presented with proteinuria, microscopic hematuria, and an increased level of serum creatinine. systemic workup revealed that the patient had bronchogenic carcinoma anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis concurrently. Despite increase in cumulative number publications on paraneoplastic glomerulopathies, awareness link between cancer ANCA-assoc...

Anti neutrophil cytoplasmic antibody (ANCA) is strongly associated with some vasculitic disorders. Behçet's disease (BD) is a systemic vasculitis of unknown etiology. In this study, ANCA was found to be positive in 8 out of 66 patients (10.2%) with BD by combination testing consisting of immunofluorescence and ELISA [one patient showed an atypical pattern by indirect immunofloresence techique, ...

Teaching NeuroImages: Myeloperoxidase–anti-neutrophil cytoplasmic antibody–positive hypertrophic pachymeningitis A woman in her 40s presents with painless monocular vision loss and is found to have optic perineuritis and dural thickening. Comprehensive laboratory testing,MRI of the brain, and dural biopsy reveal a diagnosis of myeloperoxidase–antineutrophil cytoplasmic antibody–positive hypertr...

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a distinct group of systemic with severe multi-organ involvement. It includes three types: granulomatosis polyangiitis (GPA), eosinophilic (EGPA), and microscopic (MPA). Cutaneous manifestations are present at the time presentation in around 35% cases more frequently encountered EGPA than GPA or MPA. They can also occur ...

In November 2017, the Kidney Disease: Improving Global Outcomes (KDIGO) initiative brought a diverse panel of experts in glomerular diseases together to discuss 2012 KDIGO glomerulonephritis guideline context new developments and insights that had occurred over years since its publication. During this Controversies Conference on Glomerular Diseases, group examined data disease pathogenesis, bio...