Nevus sebaceous is a hamartoma of the cutaneous structures that often presents at birth and typically involves the face and scalp. Nevus sebaceous is frequently complicated by the development of a variety of other benign or malignant neoplasms. The most frequently reported benign neoplasms are trichoblastoma and syringocystadenoma papilliferum. Malignant tumors are much less frequently observed...

A 30-year-old Caucasian female presented with a hairless plaque on her head. The patient admitted that she had this asymptomatic lesion since birth. However, the patient complained that the size of the lesion had gradually increased in the last ten years. The physical examination of the patient revealed a firm, well defined, pink-orange coloured, oval, alopecic plaque with cerebriform surface m...

Cutaneous symptoms in some patients with clinical picture of Schimmelpenning-Feuerstein-Mims syndrome can include a speckled lentiginous nevus, also known as nevus spilus. Recent investigations show that somatic heterozygous HRAS mutations are present in the sebaceous and speckled lentiginous nevus tissues of patients with combination of two nevi.

A 15-month-old girl presented with developmental delay, intractable right focal motor seizures, hyperpigmented patch on the left side of the face, facial asymmetry, and right hemiparesis (figure 1). A diagnosis of linear nevus sebaceous syndrome (LNSS) was considered. Brain MRI revealed hemimegalencephaly (figure 2). EEG showed spike/wave discharges in left occipital leads. Ophthalmologic and s...

Verrucous epidermal nevi are hamartomatous lesions of the epidermis that, unlike other epidermal nevi (such as sebaceous nevus or nevus comedonicus), are rarely associated with malignant neoplasms. The majority of squamous cell carcinoma develop in linear or multiple epidermal nevus and rarely in solitary epidermal nevus. In general, the prognosis is favorable. We report a case of well-differen...

431 ImageS nosis from basal cell carcinoma originating from the sebaceous gland. In the erythematous mass containing the nevus sebaceous, a wide excision was performed with a safety margin of 5 mm. A frozen section biopsy showed that there were no tumor cells on the resection margin. Following the resection, scalp defects of 2.5×5.0 cm in size remained (Fig. 2). The defects were reconstructed u...

Trichoblastoma is occasionally observed in association with a pre-existing nevus sebaceous in the Korean literature. However, there has been no report on the pigmented type. Herein, we report the first Korean case of a pigmented trichoblastoma arising from the nevus sebaceous on the forehead. A 28-year-old male presented with a dark nodular lesion within a yellowish plaque on the forehead. The ...

To the Editor: Nevus sebaceous (NS) is an epidermal nevus that is comprised predominantly of sebaceous glands in approximately 0.3% of newborns.[1] Clinically, it presents as a single or, less commonly, multiple yellowish‐colored plaques with overlying alopecia, usually confined on the scalp; however, it can also appear on the face, preauricular area, and neck region.[2,3] Here, we reported a c...