Nickel compounds are carcinogenic to humans and experimental animals. However, the mechanisms leading to tumor formation are still not understood since the mutagenic potential is rather weak. In contrast, nickel(II) enhances the cytotoxicity and genotoxicity in combination with several other DNA-damaging agents. To elucidate possible interactions with DNA repair processes, the effect of nickel(...

This paper presents a method for the production of high-purity anhydrous nickel(II) perrhenate. The method comprises sorption of nickel(II) ions from aqueous nickel(II) nitrate solutions, using strongly acidic C160 cation exchange resin, and subsequent elution of sorbed nickel(II) ions using concentrated perrhenic acid solutions. After the neutralization of the resulting rhenium-nickel solution...

The metal affinities of metal-sensing transcriptional regulators co-vary with cellular metal concentrations over more than 12 orders of magnitude. To understand the cause of this relationship, we determined the structure of the Ni(II) sensor InrS and then created cyanobacteria (Synechocystis PCC 6803) in which transcription of genes encoding a Ni(II) exporter and a Ni(II) importer were controll...

Nickel(II) is reported to be genotoxic, but the mechanisms underlying its genotoxicity are largely unknown. It can interfere with DNA repair and this may contribute to its genotoxicity. We studied the effect of nickel chloride on the repair of DNA damaged by UV radiation or N-methyl-N-nitro-N-nitrosoguanidine (MNNG) in human lymphocytes using the alkaline comet assay. Nickel(II) at 1 microM cau...

In earlier inhalation exposures of rabbits, nickel increased the production of surfactant by type II cells, with secondary effects on morphology and function of alveolar macrophages. Cobalt induced mainly a nodular growth pattern of the type II cells. Trivalent chromium seemed to impair the capacity of macrophages to catabolize surfactant but did not affect the type II cells. We exposed rabbits...

Up to now, researchers have proposed several synthesis methods for the preparation of β-nickel(II) hydroxide nanostructures. Most of these approaches contain harsh synthetic conditions such as multi-step processes, high temperatures and long reaction time. In this work, a novel, facile and low cost method is introduced to produce of β-Ni(OH)2 nanostructures using the gas-solution precipitation ...

Dinuclear Nickel(II) Complex, Binucleating Ligand The asymmetric unit of crystal of the title compound, [Ni2(L)(C3H 3N2)j (L = 1,3-Bis(2hydroxy-4-methoxybenzylideneamino)propan-2-ol, C3H 3N 2 = pyrazolate) contains two inde­ pendent dinickel(II) complexes. In both molecules, the nickel(II) ions are bridged by the alkoxo group of the ligand and the N atoms of the pyrazolate group. Each nickel(II...

o-Phthalonitrile couples with chelating dioxime on nickel(II), with formation of a dinuclear nickel(II) macrocyclic complex--the first representative of a new class of imine-appended macrocycles.

In this research nanoparticles of Nickel (II) Chloride were synthesized and characterized using fourier transform infrared (FT-IR) spectra. Nanoparticles of Nickel (II) Chloride were prepared by using of ball mill device. A ball mill is one kind of grinding machine, and it is a device in which media balls and solid materials (the materials to be ground) are placed in a container. In the researc...

The title compound, [Ni(C(60)H(52)N(4))], is an example of a meso tetra-substituted nickel(II) porphyrin with both meso aryl and alkyl residues. The mol-ecule exhibits a planar macrocycle with an average deviation of the 24 macrocycle atoms from their least-squares plane (Δ24) of 0.01 Å and an average Ni-N bond length of 1.960 (2) Å. The Ni(II) atom lies on a center of inversion. The structure ...