Boerhaavia diffusa roots (Punarnava mool) are in use since beginning of Ayurvd era for various therapeutic benefits. This Research Paper basily enquires into work done in the field of its Rejuvenation (Rasayan) benefits. The name Punarnava itself means ‘Rejuvenation’. In the modern allopathic terms, it has been translated as adaptogenic, immumodulatory, anti-oxidant aphrodisiac and nootropic ac...

Dementia is a brain disorder marked by cognitive dys functioning which causes loss of learning , thinking and memory .Various drugs that possess nootropic activity are used for treatment dementia but emerges side effects. To overcome these effects plants with medicinal importance came into existence. India has wide variety (Centella asiatica, Clitoria ternatea ,Ginkgo biloba, Curcuma longa etc)...

Previous studies have shown that crude ginseng extracts enhance performance on shock-motivated tasks. Whether such performance enhancements are due to memory-enhancing (nootropic) properties of ginseng, or to other non-specific effects such as an influence on anxiety has not been determined. In the present study, we evaluated both the nootropic and anxiolytic effects of the ginseng saponin Rb1....

Nootropic drugs used as a memory enhancer can improve thinking, memory, and alertness in people with Alzheimer’s disease and other disease that affect the mind. Memory is perhaps the most vital of all aspects that differentiates human beings from other animals. However, memory can become faulty due to several reasons, and in that case the person is not able to make full use of his or her potent...

Purpose: Migraine headaches and associated symptoms are prevalent medical issues. Medium-chain triglyceride (MCT)/nootropic-based compounds have demonstrated benefits in multiple domains. This study assessed the potential relief provided from a unique, high-concentration MCT/nootropic component blend on migraine frequency, duration, secondary symptoms, quality of life (QOL) during 60-day clinic...

Clitoria ternatea L. (CT) (Family: Fabaceae) commonly known as 'Butterfly pea', a traditional Ayurvedic medicine, has been used for centuries as a memory enhancer, nootropic, antistress, anxiolytic, antidepressant, anticonvulsant, tranquilizing and sedative agent. A wide range of secondary metabolites including triterpenoids, flavonol glycosides, anthocyanins and steroids has been isolated from...

Results The therapeutic response evaluated in Hamilton Scale for Depression(HAM-D), Montgomery and Äsberg Depression Rating Scale (M.A.D.R.S. ), Mini Mental State Examination (M.M.S.E.) and Global Clinical Impression (G.C.I.) scores during 8 months. In the third group who received the two drugs associated, had much better response than the others and “brain enhancer”. Conclusions The group who ...

Nootropic agents are proposed to serve as cognition enhancers. The underlying mechanism, however, is largely unknown. The present study was conducted to assess the intracellular signal transduction pathways mediated by the nootropic nefiracetam in the native and mutant Torpedo californica nicotinic acetylcholine (ACh) receptors expressed in Xenopus laevis oocytes. Nefiracetam induced a short-te...

Several 4-substituted 1-acylpiperazines, obtained by molecular simplification of 4-substituted 1,4-diazabicyclo[4.3.0]nonan-9-ones, have been synthesized and tested in vivo on the mouse passive avoidance test, to evaluate their nootropic activity. The results show that, apparently, an N-acylpiperazine group can mimic the 2-pyrrolidinone ring of 1,4-diazabicyclo[4.3.0]nonan-9-one, as the compoun...

Nootropics, natural or synthetic substances that boost brain function and cognitive abilities, were investigated in this study. Specifically, the effects of Zingiber officinale Centella asiatica extracts compared to standard nootropic piracetam. Both plant demonstrated activity contained phytochemicals like flavonoids, tannins, saponins protect from oxidative damage. Sterols such as stigmastero...