Synthetic luteinizing hormone/follicle stimulating hormone-releasing hormone (LH/FSH-RH) (50 mug) was given intravenously to six women with oligomenorrhoea and to four women with secondary amenorrhoea. Peripheral venous blood was withdrawn at regular intervals over a 24-hour period. The concentrations of LH, FSH, and oestradiol-17beta were determined by radioimmunoassay. In all subjects there w...

In this study, the effects of half, normal and double clinical doses of artesunate; artesunate/sulfadoxine/pyrimethamine; artesunate/amodiaquine and their combinants [sulfadoxine/pyrimethamine and amodiaquine] on the basal serum levels of testosterone, FSH, LH and prolactin of the guinea-pig were investigated. The results of this study showed that the agents caused significant decreases [P<0.05...

Background: Female age and basal FSH level are independently associated with IVF outcome. They are both related to the same phenomenon, namely ovarian reserve. Objective: To evaluate the effective role of serum FSH concentration at the start of treatment cycle on ART outcome. Materials and Methods: A total of 207 women undergoing IVF and ICSI cycles were included in this study. Basal FSH concen...

To establish normative data and determine the value of fluorometric AutoDELFIA assays (Wallac Oy) in the investigation of precocious puberty, we determined serum levels of LH, FSH, testosterone, and estradiol under basal and GnRH-stimulated conditions in 277 normal subjects at various pubertal stages and in 77 patients with precocious puberty. A substantial overlap was observed in basal and GnR...

We identified a new point mutation in the CYP19 gene responsible for aromatase (P450arom) deficiency in a 46,XY male infant with unremarkable clinical findings at birth. This boy is homozygote for a 1-bp (C) deletion in exon 5 of the aromatase gene causing a frame-shift mutation. The frame-shift results in a prematurely terminated protein that is inactive due to the absence of the functional re...

PURPOSE To determine if uterine artery embolization (UAE) for leiomyomata causes a change in ovarian function as measured by serial basal follicle stimulating hormone (FSH) assay. MATERIALS AND METHODS Sixty-three patients undergoing UAE for symptomatic leiomyomata had blood samples obtained on day 3 of a menstrual cycle before UAE and on day 3 during menstrual cycles 3 and 6 months after tre...

OBJECTIVE Ovarian reserve tests are commonly used to predict ovarian response in infertile patients undergoing ovarian stimulation. Although serum markers such as basal follicle-stimulating hormone (FSH) or random anti-Müllerian hormone (AMH) level and ultrasonographic markers (antral follicle count, AFC) are good predictors, no single test has proven to be the best predictor. In this study, we...

Background It is important to evaluate ovarian reserves prior to intracytoplasmic sperm injection (ICSI) treatment. The aim of this study is to determine the accuracy of anti-mullerian hormone (AMH) as a marker for ovarian reserve and to compare it with day-3 serum follicle-stimulating hormone (FSH) levels. MaterialsAndMethods In this analytic, corss-sectional study, sequential sampling was don...

background: it is important to evaluate ovarian reserves prior to intracytoplasmic sperm injection (icsi) treatment. the aim of this study is to determine the accuracy of anti-mullerian hormone (amh) as a marker for ovarian reserve and to compare it with day-3 serum follicle-stimulating hormone (fsh) levels. materials and methods: in this analytic, corss-sectional study, sequential sampling was...