We report a 42-year-old cocaine addicted female patient referred for evaluation of hard palate ulceration resulting in oro-sinus communication with difficulties in swallowing and phonation, an rhino-sinusitis. Acrylic and removable silicone prosthesis was prescribed to relieve severe functional disorders. It is essential that the patient permanently abandons cocaine use to perform surgical reco...

Fungal rhino sinusitis is a life threating, aggressive, angioinvasive infection caused by group of fungai called mucormycetes and aspergillus as well1. Spores these are present in the soil, air decaying material animal dungs. They inhaled swallowed to cause infection. It affects mainly immune compromised patients like uncontrolled diabetes (fungus grows flourish at high sugar level), organ tran...

Rhinocerebral mucormycosis is an acute fulminant opportunistic fungal infection usually seen in diabetic or immunocompromised patients. The fungi that cause mucormycosis inoculate the nasal mucosa and may spread to the paranasal sinuses, orbit, and brain. Our patient initially presented with mild ethmoid sinusitis. At that time, brain MRI and contrast-enhanced MR angiography were grossly normal...

Allergic fungal sinusitis (AFS) is a non-invasive form of allergic sinusitis, resulting from the IgE-mediated hypersensitivity reaction to fungal antigen in atopic individuals. It was first described in 1983 by Katzenstein.1 It usually follows a slow, non-aggressive course, and a wide variety of fungal agents have been implicated, with the vast majority belonging to the Dematiaceae family, such...

We document the first case of haematogenous cerebral spread in Rhizopus arrhizus rhino-orbital mucormycosis, and of posaconazole related adrenal insufficiency. A patient presenting with diabetic ketoacidosis and sinusitis was treated with right medial maxillectomy, ethmoidectomy and IV liposomal amphotericin. Orbital exenteration was performed after intraorbital spread of infection. IV caspofun...