abstract background: gastric cancer is one of the most common malignant tumors in iran. hypomethylation and/or hypermethylation of dna have been described in gastric cancer and is presumed to be an early event in this process. objective: we hypothesized that single nucleotide polymorphisms of dnmt1 gene may be associated with the genetic susceptibility to gastric cancer. methods: 200 patients a...

allele frequencies of single nucleotide polymorphisms (snps) are variable among different populations; therefore the study of snps in ethnic groups is important for establishing the clinical significance of the screening of these polymorphisms. the main goal of the research is to study the polymorphisms of cyp2c9 , cyp2c19 , vkorc1 , and slco1b1 in yakuts. genomic dna from 229 yakut subjects we...

The status of genetic diversity, adaptation to climate change or the identification genes associated with traits interest in livestock populations has been a major concern for scientists last decades. Biotechnology evolved continuously, offering new tools and methodologies analyse genomes species. Biochemical markers protein polymorphisms were used population studies many years ago, but over th...

Aim: This study aimed to investigate the relationship between severe novel coronavirus pneumonia (NCP) and hypercoagulable conditions that predispose patients thrombosis such as prothrombin gene ( F2) rs1799963 (G20210A), factor V Leiden F5) rs6025 (G1691A) PAI-1 (rs1799768). Patients: NCP-diagnosed 62 previously healthy were enrolled for investigation of thrombophilia-related polymorphisms. Ma...

Relevance . The etiological agent in the development of persistent lymphocytosis and lymphosarcoma cattle is Bovine leukemia virus Phylogenetic analysis sequenced nucleotide sequences BLV env -gene locus main, but not only, approach to pathogen genotypic classification. Metods aim study was identify single-nucleotide polymorphisms -gene, considered as diagnostically significant for SNP genotypi...