background chronic kidney disease (ckd) is a common medical condition among children and obsessive-compulsive disorder (ocd) is a frequent, chronic, costly, and disabling disorder among them. objectives the aim of this study was to investigate obsessive-compulsive disorder (ocd) in children with early stages of ckd, and to compare it with the occurrence of ocd in healthy children. patients and ...

Introduction Obsessive-compulsive disorder (OCD) is a clinical syndrome whose hallmarks are excessive, anxiety-evoking thoughts and compulsive behaviours that generally recognized as unreasonable, but which cause significant distress impairment. OCD may also occur in the context of other neuropsychiatric disorders, most commonly anxiety mood disorders. The question remains to whether these comb...

vitamin b6 is a cofactor of various enzymes influencing numerous neurotransmitters in the brain such as norepinephrin, and serotonin . since these neurotransmitters influence mood , the aim the present work to evaluate the effect of vitamin b6 on depression and obsessive compulsive behavior when coadministred with clomipramine, fluoxetine, or venlafaxine. male mice weighing 25-30 g were used. t...

Obsessive-compulsive disorder is a chronic and disabling condition that often proves to be treatment resistant. Of the patients suffering from obsessive-compulsive disorder, 10%-27% may attempt suicide at least once in their life. We report the case of a patient who presented severe obsessive-compulsive disorder symptoms and attempted suicide ingesting 25 tablets of fluoxetine (20 mg). The pati...

Neuroimaging studies of obsessive-compulsive disorder have found abnormalities in orbitofronto-striato-thalamic circuitry, including the orbitofrontal cortex, anterior cingulate cortex, caudate, and thalamus, but few studies have explored abnormal intrinsic or spontaneous brain activity in the resting state. We investigated both intra- and inter-regional synchronized activity in twenty patients...

OBJECTIVE Pathological gambling is proposed as a participant of an impulsive-compulsive spectrum related to obsessive-compulsive disorder. This study aims to contrast pathological gambling and obsessive-compulsive disorder regarding course, comorbidity, and personality, hence testing the validity of the impulsive-compulsive spectrum. METHOD 40 pathological gambling and 40 obsessive-compulsive...

Obsessive-compulsive disorder and body dysmorphic disorder have many similarities in clinical presentation. Obsessive-compulsive disorder has historically been considered an anxiety disorder, whereas body dysmorphic disorder has been grouped among the somatoform disorders. Researchers in these areas are currently debating whether the similarities warrant the inclusion of body dysmorphic disorde...

BACKGROUND Cognitive models of obsessive-compulsive disorder suggest that changes in obsessive beliefs are a key mechanism of treatments for obsessive-compulsive disorder. Thus, in the present process-outcome study, we tested whether changes in obsessive beliefs during a primarily cognitive behavioral inpatient treatment predicted treatment outcome and whether these changes mediated symptom cha...

objectives : since the symptoms of obsessive-compulsive disorder are basically culture-bound, identification and classification of the various kinds of symptoms prevalent among obsessive-compulsive patients have clinical significance. better identification of symptoms of obsession among iranian patients will result in quick and timely diagnosis of the disorder. further, it will be useful in dif...