OBJECTIVE To investigate the incidence, transition probabilities, and risk factors for obsessive-compulsive disorder (OCD) and subclinical OCD in adolescents. METHOD A two-stage epidemiological study originally designed to investigate depression was conducted between 1987 and 1989 in the southeastern United States. For the screening, a self-report depressive symptom questionnaire was administ...

Cognitive Behavioural Therapy (CBT) for preadolescent children with obsessive compulsive disorder (OCD) is typically derived from adult cognitive behavioural models of OCD; however, it unknown whether these apply to children. This systematic review examined 11 cognitive, and familial maintenance mechanisms identified OCD descriptions how family factors may maintain applied symptoms/disorder (OC...

The relationship between disgust propensity (DP) and obsessive–compulsive disorder (OCD), particularly with contamination-related OCD symptoms, has been widely recognized. The relationship between trait guilt (TG) and OCD has been less investigated, although some studies have explored the role of guilt in OCD, and found that it may precede, motivate or be a consequence of OCD symptoms. The pres...

BACKGROUND Neuro-imaging studies in OCD report the orbitofrontal cortex to be functionally abnormal. As these areas are presumed to be involved in decision making, studying this behavior in OCD may provide further insight into the cognitive deficits accompanying the disorder. METHODS Performance of 27 drug-free OCD patients and 26 healthy volunteers was compared on the decision making task of...

OBJECTIVE There is mixed evidence as to whether patients with obsessive-compulsive disorder (OCD) have excessive attentional engagement and emotional response to OCD-related stimuli in the environment. Here we investigate the occurrence of an attentional bias toward specific OCD-related stimuli and its relationship with obsessive-compulsive symptom dimensions. METHODS Forty-eight patients wit...

We studied the behavioral, cognitive, and neuroimaging characteristics of obsessive-compulsive disorder (OCD) in 13 patients with focal brain lesions (acquired OCD) and compared their clinical features and the severity of obsessive and compulsive (OC) symptoms with patients with idiopathic OCD. Both OCD groups were further compared with matched normal controls on a series of neuropsychological ...

We examined whether the patients with Bipolar Disorder (BD) and Obsessive-Compulsive Disorder (OCD) comorbidity may represent a distinct form of BD. The subjects diagnosed with BD (n=48), OCD (n=61), and BD with OCD (n=32) were compared in terms of several socio-demographic and clinical characteristics. Previous history of suicidal attempts was more likely to be higher in BD-OCD group compared ...

OBJECTIVE Resolving the entangled nosological dilemma of whether obsessive-compulsive disorder (OCD) with and without schizophrenia (schizo-OCD and OCD, respectively) are two independent entities or whether schizo-OCD is a combined product of its parent disorders. METHODS Studying motor activity in OCD and in schizo-OCD patients. Performance of the patients was compared with the performance o...

BACKGROUND/PURPOSE Long-term outcome of patients with severe obsessive-compulsive disorder (OCD) and schizotypal features has been rarely studied. We investigated this issue in this retrospective pilot study. METHODS Twenty-two patients with severe OCD and schizotypal features were identified by chart review. Another 22 OCD patients without schizotypal features (OCD-NS) served as the comparis...