Schematic illustration of redox-sensitive, octadecyl chain-bearing PEGylated diaminobutyricpoly(propyleneimine)-based dendrimersomes (DAB-PEG-S-S-ODT) for drug and gene delivery to cancer cells.

SUMMARY The current study aims to use an oral lipophilic prodrug approach to promote the delivery of a model immunomodulator, mycophenolic acid (MPA) to the lymphatic system to facilitate enhanced uptake into lymphocytes. The project builds on recent studies demonstrating that targeted drug delivery to lymphocytes in the lymphatics may enhance immunomodulatory effects [1,2]. Two types of lipoph...

The authors describe the preparation of a C18 bonded phase using silica chemically modified with tetraisopropyl orthotitanate. The product was reacted with ocadecyltrimethoxysilane to yield a reversed phase. The chromatographic performance of this phase was evaluated for the separation of various test mixtures containing polar, nonpolar, and basic compounds, and its stability at pH 9 and 10 was...

The fabrication and characterization of over millimeter (mm)-scale Au plasmonic structures are reported. Fishnet structures of Au are fabricated by the "bottom-up (direct deposition of alkanethiol)" and "top-down (wet-etching of Au)" combined approach using massively parallel dip-pen nanolithography (DPN). An array of two-dimensional (2D) parallel 55,000 pens was used for the DPN writing of 1-o...

Since the 1500s, Mayan language and glyphic systems have been romanticized by Eurocentric interpretations. In recent years, many anthropological works have perpetuated these myths by presenting inaccurate analyses of Maya linguistics. Rather than showing the Maya as an advance and civilized people, these texts promoted a weak, barbarous Maya who could be easily manipulated by European culture, ...

phenytoine derivatives were synthesized , via the  pinacol condensation  with the  reaction of 1,3- diphenyl- propane- 1,3- dione (benzyl) analogs with urea or thiourea in presence of slica gel and solid KOH as Solid phase catalyst  in the mortar / pestle at room temperatures. The reaction was completed at short reaction times (approximately 15min) and pure products were obtained with high yiel...

Amphiphilic random and block terpolymers bearing PEG chains, crystalline octadecyl groups, amorphous oleyl groups were designed to control crystallization microphase separation in the solid state.

We present a novel ‘‘dynamic learning’’ approach for an intelligent image database system to automatically improve object segmentation and labeling without user intervention, as new examples become available, for object-based indexing. The proposed approach is an extension of our earlier work on ‘‘learning by example,’’ which addressed labeling of similar objects in a set of database images bas...

OBJECTIVES The main objective of this study is to describe the methods and design of the survey of living conditions in the Arctic (SLiCA), relevant participation rates and the distribution of participants, as applicable to the survey data in Alaska, Greenland and Norway. This article briefly addresses possible selection bias in the data and also the ways to tackle it in future studies. STUDY...