The aim of this study was to investigate the corneal alterations occurring in rheumatoid arthritis (RA) patients compared with healthy subjects and to define the presence of biomechanical alterations in cornea accompanying dry eye disease, the most common ocular manifestation of RA. Forty-seven RA patients and 40 control cases without any known systemic or ocular diseases were included in this ...

Funduscopy is one of the most commonly used diagnostic tools in the ophthalmic practice, allowing for a ready assessment of pathological changes in the retinal vasculature and the outer retina. This non-invasive technique has so far been rarely used in animal model for ophthalmic diseases, albeit its potential as a screening assay in genetic screens. The zebrafish (Danio rerio) is well suited f...

AIMS To investigate the source of ocular blood flow alterations in glaucoma. METHODS In 56 patients with open angle glaucoma, blood flow parameters were obtained from both eyes in the ophthalmic and central retinal artery by means of colour Doppler imaging, as well as in the choroidal circulation and the neuroretinal rim of the optic nerve by means of laser Doppler flowmetry. Based on these h...

Physiological changes during pregnancy involve changes to the interior of the eye and to the outer ocular surface. Among the pathological alterations, several are related to gestational hypertension, such as, central serous retinopathy and occlusive vascular diseases, in addition to the evolution of preexisting pathologies. Likewise, the administration of ocular drugs, depending on the route, m...

CASE REPORTS We report two cases of hypertrophic pachymeningitis with ophthalmological disturbances. One patient suffered from hypertrophic pachymeningitis supposedly secondary to a focal neurosarcoidosis and had a sixth nerve paresis. The second patient suffered from a diffuse idiopathic hypertrophic chronic pachymeningitis (a rare form) and displayed disturbances in vision and ocular motility...

Previous studies have shown ocular haemorrhages in choline-deficient rats. The aim of this paper is to study further the relationship between ocular and renal lesions and biochemical alterations in rats fed a choline-deficient diet. Fifty one weanling male Wistar rats, were divided into two groups. Thirty one of them were fed a choline-deficient diet and the rest was fed a choline-supplemented ...