INTRODUCTION The annual rate of recreational overdose (OD)-related death is increasing exponentially, making unintentional overdose the leading cause of injury-related death in America. Unfortunately, little attention in the resuscitation community has focused on the post-arrest care of this rapidly growing population. METHODS We included patients presenting between January 2009 and February ...

OBJECTIVE The requirement to inject current basal insulin analogs at a fixed time each day may complicate adherence and compromise glycemic control. This trial evaluated the efficacy and safety of varying the daily injection time of insulin degludec (IDeg), an ultra-long-acting basal insulin. RESEARCH DESIGN AND METHODS This 26-week, open-label, treat-to-target trial enrolled adults (≥18 year...

AIM To determine the epidemiology of intentional antidepressant drug overdose (OD), over an extended time period, in Victoria, Australia. METHODS Retrospective epidemiological study of all cases reported to the Victorian Emergency Minimum Dataset (VEMD) January 1998 to December 2007 and calls to the Victorian Poisons Information Centre (VPIC) June 2005 to September 2008. RESULTS 5467 VEMD c...

The outer domain (OD) of human immunodeficiency virus (HIV)-1 gp120 represents an attractive, if difficult, target for a beneficial immune response to HIV infection. Unlike the entire gp120, the OD is structurally stable and contains the surfaces that interact with both the primary and secondary cellular receptors. The primary strain-specific neutralizing target, the V3 loop, lies within the OD...

Vehicle re-identification using Bluetooth (BT) signal data has emerged as an effective and economical means for collecting traffic data including Origin Destination (OD) information which is crucial for transportation planning. Direct vehicle tracking based on Time-Lapse Aerial Photography (TLAP) is also increasingly used for OD studies. Neither technique has previously been validated, so the o...

Let $G$ be a finite group and $pi(G)$ be the set of all the prime‎ ‎divisors of $|G|$‎. ‎The prime graph of $G$ is a simple graph‎ ‎$Gamma(G)$ whose vertex set is $pi(G)$ and two distinct vertices‎ ‎$p$ and $q$ are joined by an edge if and only if $G$ has an‎ ‎element of order $pq$‎, ‎and in this case we will write $psim q$‎. ‎The degree of $p$ is the number of vertices adjacent to $p$ and is‎ ...

Oldenlandia diffusa (OD) is commonly used with various diseases such as cancer, arthritis, and autoimmune disease. Liver cirrhosis is a predominant risk factor for hepatocellular carcinoma (HCC). Here, we show that the therapeutic effect of OD, which was investigated both in vitro and chemically, induced HCC model. OD significantly enhanced apoptosis and antiproliferative activity and reduced m...