OBJECTIVES Reactive oxygen species (ROS) induced lipid peroxidation is associated with sperm function. Malondialdehyde (MDA) concentration and glutathione peroxidase (GPx) activity represent the lipid peroxidation and spermicidal antioxidant, respectively. We aimed to evaluate the relationship of MDA and GPx levels with sperm parameters. PATIENTS AND METHODS Specimens were divided into two gr...

OBJECTIVE To determine whether semen and plasma presepsin values measured in men with normozoospermia and oligoasthenospermia undergoing invitro-fertilization would be helpful in predicting ongoing pregnancy and live birth. METHODS Group-I was defined as patients who had pregnancy after treatment and Group-II comprised those with no pregnancy. Semen and blood presepsin values were subsequentl...

Introduction: Clomiphene, a selective estrogen receptor modulator (SERM), is drug which primarily used for the treatment of anovulatory infertility in female patients. Although as an off-label use, some authorities and physicians use this idiopathic oligoasthenospermia male Clomiphene has two isomers multiple metabolites, its cis isomer (Zuclomiphene) can be detected urine long eight months cas...

Aim: To evaluate the efficacy of an antioxidant herbomineral formulation, Addyzoa (Charak Pharma Pvt. Ltd., Mumbai, India) in oligospermia in comparison with Ubiquinone (Coenzyme Q10). Methods: A double-blind, randomised controlled trial was conducted at Dr Vaze’s clinic, Mumbai. A total of sixty patients, 30 in each group, were studied. Cap Addyzoa was administered in a dose of two capsules tw...

Introduction: Our aim was to compare the nuclear DNA integrity of the spermatozoa from infertile men with abnormal semen parameters with that from normospermic fertile men, and to evaluate the relationship between the sperm DNA integrity and semen parameters. Materials and Methods: Thirty ejaculate samples with abnormal semen analysis and 30 ejaculates with normal semen parameters were randomly...

With the increasing success of multimodality anticancer therapy, most men of reproductive age will survive their malignancy. Reproductive function is a principal concern of these men. Health-care providers are shifting the focus of oncologic care toward improving the quality of life in cancer patients, particularly with regard to fertility. For unknown reasons, fertility and sexual function are...

Background: Infertility is defined as failure to conceive within one or more years of regular unprotected coitus. The infertility state is dependent on the female factor as well as masculine factor; an altered masculine factor is designated when any cause or causes of infertility reside in the male. The masculine factor as a cause of infertility is present in 40-50% of cases hence the importanc...