نتایج جستجو برای: oligolamellar vesicles
تعداد نتایج: 41864 فیلتر نتایج به سال:
Introduction: Inflammatory bowel disease(IBD) is caused by genetic, environmental, microbial and immune factors. IBD has two primary forms: Ulcerative colitis and Crohn´s disease. The incidence of IBD has significantly increased over the last few decades. Given that patients have poor response to drug treatments or are resistant to drug therapies, new therapies are needed for gastrointestinal i...
Background & Aims: Extracellular vesicles are double phospholipid layer vesicles releasing from several cells. These particles contain bio-molecules including mRNA, miRNA, DNA, proteins, and lipids which play a pivotal role in the cell to cell communication. Once delivered, they participate to change target cell function, fate, morphology, differentiation, and growth. The present study is a re...
Positively charged, oligolamellar liposomes were able to enter the pea pollen grains during the germination process in vitro. Large, identifiable liposomes could be found at a low frequency in living, germinated pollen grains and pollen tubes. Protoplasmic streaming inside the germinated pollen apparatus, where it appears as moving strands, exerts violent, formative effects on the liposomes. Up...
Multilamellar vesicles (noisome) of polyoxyethylene alkyl ether surfactants (Brij 52, 72, 76 and 92) were prepared using classic film hydration method. Vesicle formation ability of the surfactants was assessed in presence or absence of cholesterol. All used surfactants formed vesicles in the absence of cholesterol. Recombinant human insulin was used as a model protein drug to investigate encaps...
Purpose: This work studies possible role of FOS proteins, retinoic acid (RA) and mitogens during optic vesicle development in vitro. Materials and Methods: Fos was detected as a product of 55-62 kDa in optic vesicles via electrophoretic procedures. Incubation (24hr) of optic vesicles with RA 25nM and mitogens(serum10%,insulin2.5%) on the day 9.5 of gestation revealed that Fos was induced by mi...
background: extracellular vesicles are particles ranged from 30 nm to 5µm and subcategorized into three groups; exosomes, microvesicles and apoptotic bodies, each of which have different biological impact. lack of a standard method for the detection and isolation of mvs has led to a challenging issue that is a worth considering. in this study, we isolated mvs from the conditioned medium of uc-m...
background: the study was performed to investigate the effects of morphine dependency and morphine withdrawal on the reproductive system of adult male rat(wistar). methods: 32 adult male rat divided into 5 groups. animals in the control group (n=8) received normal saline (1ml/kg) twice daily subcutaneously for 30 consecutive days. animals in dependent group (n=8) received morphine (10mg/ml/kg)...
Extracellular vesicles were initially known as cellular waste carriers, while recent studies demonstrate that extracellular vesicles play important biological roles in all aspects of life-from single cells to mammalians. Their pathophysiological roles in some diseases like cancer are being decoded. Extracellular vesicles are divided into some classes and there are different strategies to isolat...
Thermodynamic features related to preparation and use of self-assemblies formed between multilamellar and unilamellar zwitterionic liposomes and polynucleotides with various conformation and sizes are presented. The divalent metal cation or surfactant-induced adsorption, aggregation and adhesion between single- and double-stranded polyribonucleotides and phosphatidylcholine vesicles was followe...
Thermodynamic features related to preparation and use of self-assemblies formed between multilamellar and unilamellar zwitterionic liposomes and polynucleotides with various conformation and sizes are presented. The divalent metal cation or surfactant-induced adsorption, aggregation and adhesion between single- and double-stranded polyribonucleotides and phosphatidylcholine vesicles was followe...
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