Oligomenorrhea is a polyetiological disease, and in the adolescent population most often considered as physiological condition, due to lack of clear relationship with any particular somatic or gynecological pathology. Hormonal research, cases, not informative. In this regard, it relevant search for molecular biological markers that allow diagnosing disease early stages its development. Modern s...

OBJECTIVE To study the independent associations of polycystic ovary syndrome (PCOS), and its 2 components, hyperandrogenism and anovulation, with coronary artery calcification (CAC) and carotid artery intima-media thickness (IMT). APPROACH AND RESULTS At the year 20 of the Coronary Artery Risk Development in Young Adults (CARDIA) study, a population-based multicenter cohort of young adults, w...

A urine sample submitted for a urinary calcium-to-creatinine ratio was visually clear but deep orange in color (Fig. 1, left). Acidification of the sample to pH 2.0 with HCl prior to analysis produced a color change in the sample from orange to deep red (Fig. 1, right). The 16-year-old female patient had a history of polycystic ovarian syndrome, oligomenorrhea, and vitamin D deficiency and a su...

Polycystic ovarian syndrome (PCOS), also known as SteinLeventhal syndrome, is a common gynecological disorder characterized by hypergonadotrophism, hirsutism, obesity, oligomenorrhea and commonly associated with infertility. PCOS is a complex clinical picture and presents a multifaceted etiology related to imbalance of the hypothalamic-pituitary-adrenal (HPA) axis, thyroid involvement and metab...

Introduction Perimenopause refers to the period during which women’s body makes natural transition menopuse, marking end of reproductive years. is characterized by several symptoms including irregular menstrual cycles, hot flushes, and sleep disturbances. Moreover, perimenopasue, women with oligomenorrhea need midwifery care in order overcome effects a prolonged cycle such as feeling anxiety. T...

Our preliminary family studies have suggested that some female first-degree relatives of women with polycystic ovary syndrome (PCOS) have hyperandrogenemia per se. It was our hypothesis that this may be a genetic trait and thus could represent a phenotype suitable for linkage analysis. To investigate this hypothesis, we examined 115 sisters of 80 probands with PCOS from unrelated families. PCOS...