نتایج جستجو برای: omeprazole
تعداد نتایج: 3166 فیلتر نتایج به سال:
Gastric ulcer is a serious condition that results from the wearing/tearing of stomach mucosa. A physiological equilibrium maintained between mucosal defense and aggressive factors. In this study, effectiveness medicinal plants (Hypericum perforatum) in management gastric was compared to omeprazole, well-known drug for ulcer. This study involved numerous groups male rats comprising following: fi...
BACKGROUND The ideal medication for acid-related diseases should have a rapid onset of action to promote hemostasis and cause efficient resolution of symptoms. The aim of our study was to comparatively investigate the inhibitory effect on gastric acid secretion of a single oral administration of omeprazole plus mosapride with that of omeprazole alone. METHODS Ten Helicobacter pylori-negative ...
BACKGROUND AND PURPOSE A triple therapy with omeprazole, amoxicillin (INN, amoxicilline), and clarithromycin is widely used for the eradication of Helicobacter pylori. Omeprazole and clarithromycin are metabolized by CYP2C19 and CYP3A4. This study aimed to elucidate whether clarithromycin affects the metabolism of omeprazole. METHODS After administration of placebo or 400 mg clarithromycin tw...
PURPOSE The stability and viscosity of preparations of a commercially available, flavored, immediate-release powder for oral suspension (omeprazole-sodium bicarbonate) during refrigerator and room temperature storage were investigated. METHODS Omeprazole-sodium bicarbonate 20-mg packets were suspended to initial omeprazole concentrations of 0.6 and 2 mg/mL, and omeprazole-sodium bicarbonate 4...
background: omeprazole is metabolized predominantly by cyp2c19, a polymorphically expressed enzymes that show marked interindividual and interethnic variation. these variations cause a substantial differences that have been reported in the pharmacokinetics of omeprazole. the aim of the present study was to evaluate the pharmacokinetic parameters of omeprazole in a random iranian population. met...
UNLABELLED Omeprazole is a well studied proton pump inhibitor that reduces gastric acid secretion. This review examines its use in Helicobacter pylori infection, gastro-oesophageal reflux disease (GORD) with or without oesophagitis and gastrointestinal damage caused by nonsteroidal anti-inflammatory drugs (NSAIDs). Optimal omeprazole regimens for anti-H. pylori therapy are those that administer...
background: endoscopic therapies can decrease the morbidity of patients with high risk peptic ulcer. the aim of this study was to evaluate the beneficial effects of oral omeprazole therapy in patients with bleeding peptic ulcer who received combined endoscopic treatment (epinephrine injection and argon plasma coagulation). materials and methods: eighty six patients with bleeding from gastric, d...
conclusions b. oleracea demonstrated similar anti-inflammatory properties to omeprazole in rats with gerd. however, omeprazole also demonstrated genotoxic and cytotoxic effects in rats without gerd. results rats with gerd developed esophagitis and esophageal squamous cell carcinoma. b. oleracea and omeprazole-treated gerd rats presented significantly decreased inflammation in relation to non-tr...
Hyperoxia contributes to lung injury in experimental animals and bronchopulmonary dysplasia (BPD) in preterm infants. Cytochrome P4501A (CYP1A) enzymes, which are regulated by the aryl hydrocarbon receptor (AhR), have been shown to attenuate hyperoxic lung injury in rodents. Omeprazole, a proton pump inhibitor, used in humans to treat gastric acid-related disorders, induces hepatic CYP1A in vit...
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