PURPOSE To examine the roles of genetic and environmental factors in the optic disc in a classic twin study. METHODS Five hundred six pairs of twins were recruited to participate from the Twins U.K. Adult Twin Registry at St. Thomas' Hospital, London. Photographs of the optic disc were obtained, and the covariance of optic disc, cup, and rim areas within monozygotic (MZ) and dizygotic (DZ) pa...

PURPOSE To examine the influence of body height, body weight, and body mass index (BMI) on optic disc parameters in a population-based study. METHODS The Singapore Malay Eye Study examined 3280 persons of Malay ethnicity, aged 40 to 80 years, of whom 2329 (71.0%) had reliable retinal scanning confocal laser tomography images for analyses. Intraocular pressure (IOP) was ascertained by Goldmann...

PURPOSE To compare the optic disc parameters of glaucomatous eyes to those of non-glaucomatous eyes with large discs. METHODS We studied 225 consecutive eyes with large optic discs (>2.82 mm2): 91 eyes with glaucoma and 134 eyes without glaucoma. An eye was diagnosed with glaucoma when visual field defects were detected by the Humphrey Field Analyzer. All of the Heidelberg Retina Tomograph II...

Background: Stereoscopic assessment of the optic disc morphology is an important part of the care of patients with glaucoma. The aim of this study was to assess stereoviewing of stereoscopic optic disc images using an example of the new technology of autostereoscopic screens compared to the liquid shutter goggles. Methods: Independent assessment of glaucomatous disc characteristics and measurem...

PURPOSE To quantitatively evaluate the change in the optic disc topographic parameters associated with reduction in the intraocular pressure (IOP) after trabeculectomy in adult patients with glaucoma. METHODS A series of 22 patients (mean age: 45.7+/-15.1 years) with several types of glaucoma were examined for various parameters of optic disc before and after trabeculectomy. Cup area, cup-to-...

AIM To study optic disc topographic parameters in normal cynomolgus monkeys by Heidelberg retina tomograph (HRT). METHODS 12 optic disc topographic parameters were investigated in 36 normal eyes in 18 male monkeys. Mean (SD) and interocular differences were obtained for each parameter from three independent measurements made during a 1 week period. Correlations among the topographic parameter...

This paper presents a novel approach to the fast localization and extraction of optic disc from fundus images of the human retina. Optic disc continues to be a major landmark for fundus image registration and is indispensible for the understanding of retinal fundus images. For the detection of optic disc, we first decompose the image into its bit planes. The lower order bit planes are found to ...

PURPOSE To investigate the effects of age, eye refraction, and disc area on topographic parameters of the optic nerve head in normal volunteers, using the Heidelberg Retina Tomograph. METHODS Seventy-seven eyes of 77 normal volunteers were examined by scanning laser tomography. The topographic parameters analyzed were disc area, cup area, cup/disc area ratio, rim area, cup volume, rim volume,...

BACKGROUND The parameters of the optic disc and peripapillary retinal nerve fibre layer (pRNFL) in children may vary with disease processes that contribute to visual impairment and blindness and so could be useful as an objective measure in at-risk children. There is no standardised reference for the normal parameters of the optic disc and pRNFL in children; however, there are a large number of...

Background: The early diagnosis of glaucoma is a global problem. Physiologic large cup (PLC) with an abnormally high cup/disc ratio may be confused with changes of the optic disc in early glaucoma. However, fewer reports are available regarding PLC in normal population. Heidelberg Retina Tomograph (HRT) can provide quantitative topographic parameters of the optic discs and be used widely. Conse...