Background and aim: Pemphigus vulgaris (PV) is an autoimmune disorder that can clinically manifest as oral mucosal ulcers. Several researchers believe that the level of female sex hormones such as estrogen and progesterone could be effective in the pathogenesis and growth of lesions such as desquamative gingivitis. Studies related to oral ulcers have revealed contradictory results regarding the...

It is speculated more that 400 bacterial species reside in the ora1 eavity and the integrity of oral mucosa is maintained in such an environment. Oral mucosal cells such as epithelial cells and fibroblasts express a wide variety of receptors and preduce many immune regulators i, e., cytokines, chemokines, proteases, and chemical mediators and actively participate in host defenses by interacting...

It is speculated more that 400 bacterial species reside in the ora1 eavity and the integrity of oral mucosa is maintained in such an environment. Oral mucosal cells such as epithelial cells and fibroblasts express a wide variety of receptors and preduce many immune regulators i, e., cytokines, chemokines, proteases, and chemical mediators and actively participate in host defenses by interacting...

The human amniotic membrane (AM) is a thin intrauterine placental membrane that is highly biocompatible and possesses anti-inflammatory and anti-scarring properties. Using AM, we developed a novel method for cultivating oral mucosal epithelial cell sheets. We investigated the autologous transplantation of oral mucosal epithelial cells cultured on AM in patients undergoing oral surgeries. We obt...

The present study was carried out to test the colonic mucosal response of rats to oral supplementation with Lactobacillus fermentum BGHI14 and to correlate the tissue reaction to trinitrobenzenesulfonate (TNBS)-induced colitis with mucosal barrier alterations caused by bacterial ingestion. An immune cell-mediated reaction of healthy colonic tissue was noticed after bacterial feeding. After prol...

Statement of the problem: Nowadays leishmaniasis is a common infectious disease around the world which is caused by a protozoan parasite named Leishmania. This parasite is transmitted to human by an infected female sand fly. This disease has three clinical forms; mucosal forms are rare in Iran. Purpose: The purpose of this study was to report a case of leishmaniasis with lip and oral mucosal in...

OBJECTIVE To study the severity of symptoms and estimate the prevalence of oral mucosal lesions in a non-referral adult Swedish population, as registered by general dental practitioners. This study also aims to evaluate the possibility of dental practitioners collecting large quantities of reliable and accurate clinical data on oral mucosal lesions. STUDY DESIGN Data from 6,448 adult Swedish ...

background there is a potential risk for malignancy in patients with diabetes mellitus. theoretically, a noninvasive method for detection of precancerous changes can be conducted on oral exfoliated cell smears. objectives in this study, the immunocytochemistry of p53 in exfoliated oral mucosal cells in patients with type 2 diabetes was investigated. patients and methods oral mucosal smears were...

BACKGROUND AND AIM: Epidemiological studies have established a wide variation in the prevalence of oral lesions in different population. Officially oral mucosa diseases can occur in 25-50% of cases, depending on the population to which the survey was conducted. We examined the relationship between oral mucosal lesions, tongue pH level, gingivitis, oral hygiene, and oral health behaviors in stud...