Oral instant membranes can be quickly wetted by the patient’s saliva and dissolved/disintegrated in mouth without need for drinking water chewing, exhibiting great promise patients from children to elderly who have difficulties with swallowing. However, reported oral load release only one single drug, which greatly hinders their potential applications. Herein, we employ a sequential electrospin...

Oral delivery of insulin may significantly improve the quality of life of diabetes patients who routinely receive insulin by the subcutaneous route. In fact, compared with this administration route, oral delivery of insulin in diabetes treatment offers many advantages: higher patient compliance, rapid hepatic insulinization, and avoidance of peripheral hyperinsulinemia and other adverse effects...

The delivery method of [continuous (CONT) vs. every other day or intermittent (INT)] a glucogenic precursor (GP) which was contained glycerin (500 g/kg), mono-propylene glycol (250 g/kg), calcium propionate (150 g/kg), niacin (1 g/kg) and sulfate-Co (350 mg/kg) on performance, selected blood metabolites and liver enzymes were evaluated. Twenty-four multiparous Holstein fresh cows were ...

The vaccine Bacillus of Calmette Guérin (BCG) was originally developed in France as an oral vaccine against tuberculosis. The oral use of this vaccine was replaced by the parenteral route in almost all countries after the Lubeck disaster. In contrast, Brazil retained the oral delivery of the vaccine until the mid-seventies when it was replaced by the intradermal route. This change in route of d...

1381-5148/$ see front matter 2010 Elsevier Ltd. A doi:10.1016/j.reactfunctpolym.2010.10.002 ⇑ Corresponding authors. Addresses: Biomedical Re of Science and Technology, 39-1 Hawolgok-dong, S Republic of Korea. Tel.: +82 2 880 9179 (K. Park). Purd of Biomedical Engineering, 206 S. Martin Jischke Driv USA. Tel.: +1 765 494 7759 (K. Park). E-mail addresses: [email protected] (K (K. Park). Adv...

Biopolymers are promising materials in the delivery of protein drugs due to their compatibility, degradation behavior, and nontoxic nature on administration. On suitable chemical modification, these polymers can provide better materials for drug delivery systems. Nanostructured drug carriers allow the delivery of not only small-molecule drugs but also of nucleic acids and proteins. The use of b...

background and objectives: preterm labor is a serious problem in obstetrics, accounting for 70% of perinatal mortality. high sensitive c - reactive protein (hs-crp) is a sensitive marker of inflammation. our aim in this study was to determine amniotic fluid hs-crp concentration and its correlation with pre-term delivery.   materials and methods: this prospective study was conducted on 90 pregna...

objective: to investigate the clinical advantage of several prognostic factors for predicting preterm delivery. materials and methods: eighty and six patients with a singleton pregnancy admitted to vali-asr hospital underwent genetic amniocentesis between the 15th and 23th weeks were included in this study. maternal serum c-reactive protein (crp), transvaginal sonographic measurement of cervica...