introduction: a rare case of basaloid squamous cell carcinoma (bscc) of the larynx, which has not been previously reported, is described. case report: a 60-year-old man was presented to the otolaryngology department with progressive dyspnoea and dysphagia to solids for over a period of 1 week. direct laryngoscopy revealed a tumour at the laryngeal aspect of the epiglottis, which prolapsed into ...

Background: Oral squamous cell carcinoma is the sixth most common malignancy in the world today.  ING1b/p33 is a newly-discovered tumor suppressor which enhances p53 activity. Transfer of p33 protein from nucleus to cytoplasmic compartment has been previously reported in leukemias. The objective of this study was to determine the correlation between p33ing1b cytoplasmic transfer and lymph node ...

Background & Aims: Leukoplakia is the most common premalignant or potentially malignant lesion of the oral mucosa and its potentiality for malignant transformation is unpredictable. The aim of the present study was to evaluate p53 expression in normal oral epithelium, leukoplakia and oral squamous cell carcinoma. Methods: The standard Biotin streptavaidin peroxidase immunohistochemical staining...

background: oral squamous cell carcinoma is the sixth most common malignancy in the world today.  ing1b/p33 is a newly-discovered tumor suppressor which enhances p53 activity. transfer of p33 protein from nucleus to cytoplasmic compartment has been previously reported in leukemias. the objective of this study was to determine the correlation between p33ing1b cytoplasmic transfer and lymph node ...

snus (nass) is a form of snuff used in a similar manner to american dipping tobacco, but it does not typically result in a need for spitting. possible hazards associated with this material include malignant and premalignant lesions in the oral cavity and gastrointestinal tract. the use of smokeless tobacco has increased in the middle east in recent decades, particularly among teenagers and youn...

the purpose of the present study was to estimate the frequency of hpv dna in four groups of oral lesions, including oral squamous cell carcinoma. sixty paraffin-embedded oral tissue samples were examined for the presence of hpv dnas using the pcr technique. these specimens were obtained from patients with oral squamous cell carcinoma (oscc), leukoplakia, oral lichen planus (olp), and pyogenic g...

Background: Oral cancer is among the 10 most common cancers worldwide with an increasing global incidence. Compromised antioxidant defense system plays a role in occurrence of cancer. This study evaluated the salivary antioxidant level of oral cancer patients compared to a control group. Patients and Methods: This case-control study was conducted on 22 oral squamous cell carcinoma patients pre...

the role of oxygen free radicals in the initiation, promotion and progression of carcinogenesis and the protective role of anti-oxidant defenses has been the subject of much speculation in the recent past with conflicting reports in the literature. in recent years, increasing experimental and clinical data have provided compelling evidence for the involvement of oxidative stress in a large numb...