Precancerous lesions of oral mucosa, known as potentially malignant disorders in recent years, are consists a group diseases, which should be diagnosed the early stage. Oral leukoplakia, submucous fibrosis, and erythroplakia most common mucosal diseases that have very high transformation rate.

To estimate the hemoglobin and serum iron levels in patients diagnosed with oral submucous fibrosis and to compare the values with that of the healthy subjects and with patients diagnosed of iron deficiency anemia Patients reporting to the Department of Oral Medicine and Radiology, The Oxford Dental College, Hospital and Research Center, Bengaluru, who were clinically and histopathologically di...

Areca nut, commonly called as betel nut or supari, is a fruit of areca catechu palm tree, which is native of South Asia and Pacific Islands. The seed or endosperm is consumed fresh, boiled or after sun drying or curing. Chewing areca nut is thought to have central nervous system stimulating effect and along with this it is known to have salivary stimulating and digestive properties. According t...

Oral submucous fibrosis (OSMF) is characterized by excessive deposition of collagen in the connective tissue leading to secondary changes in epithelium. It has multifactorial etiology. This case reports Oral Submucous Fibrosis occurring in a 28 year old male with a history of betel quid chewing. Various treatment modalities are proposed such as nutritional support, immunomodulatory drugs, physi...

Oral Submucous fibrosis is a chronic progressive debilitating disease and often considered to be a potentially malignant disorder. Development of epithelial dysplasia in oral sub mucous fibrosis is debatable and the role of epithelium and connective tissue bed in its initiation, progression and promotion had been studied by various authors. Changes in epithelium of oral sub mucous fibrosis are ...

Oral submucous fibrosis (OSMF), which presents with a severe degree of trismus, is a great surgical challenge. The surgical procedures include excision of fibrous bands with or without coverage of the surgically created defect. The use of vascularised flaps such as the palatal pedicled flap, tongue flaps, use of buccal fat pad and nasolabial flaps are becoming increasingly popular. We present a...

Aim: Altered lipid profile patterns have been associated with pre-malignancies and malignancies because lipids play a vital role in the maintenance of cell integrity. The present study evaluated alterations in serum lipid profile in untreated patients with oral submucous fibrosis (OSF) and compared the changes in serum lipid profiles among various histological grades of OSF. Materials and metho...

Background: Oral Submucous Fibrosis is a potentially malignant disorder well known for its chronic and resistant nature. The conservative drug treatment that is currently available for this disorder is clearly inadequate. The aim of the study was to evaluate the efficacy of oral lycopene therapy when used in combination with conventional intralesional steroid therapy in the management of oral s...

Oral submucous fibrosis is a chronic, progressive, disabling and scarring disease that affects the entire oral cavity, sometimes the pharynx, and rarely the larynx which predominantly affects the people of southeast Asia. It is characterized by blanching and stiffness of the oral mucosa, which causes progressive limitation of mouth opening and intolerance/ burning sensation to hot and spicy foo...

Background: Nucleolar organizer regions (NORs) are defined as nucleolar components containing a set of argyrophilic proteins, which are selectively stained by silver methods. After silver-staining, the NORs can be easily identified as black dots exclusively localized throughout the nucleolar area and are called AgNORs. AgNORs have been used to assess biologic aggressiveness of lesions, such as ...