Organ shortage is the greatest challenge facing the field of organ transplantation today. A variety of approaches have been implemented to expand the organ donor pool including live donation, a national effort to expand deceased donor donation, split organ donation, paired donor exchange, national sharing models and greater utilization of expanded criteria donors. Increased public awareness, im...

Organ transplantation is a safe and often life-saving treatment option for patients suffering from organ failure. Advances in operating techniques, basic understanding of immunology, rejection prophylaxis/therapy and, last but not least, organ preservation have paved the way for long-term success in transplantation medicine. However, the shortage of donor organs remains a fundamental problem. F...

LA TRANSPLANTATION D’ORGANES HUMAINS VITAUX SAUVE LA VIE de quelque 1500 Canadiens par année, ou l’améliore de façon spectaculaire. Ces interventions délicates, qui ne sont plus expérimentales, évitent aussi au système de soins de santé des millions de dollars de frais d’hospitalisation, de dialyse et autres. Or, malgré l’appui général de la population, le Canada enregistre un des taux les plus...

Deceased organ donation is much less prominent in Japan than it is in Western and other Asian countries. Because a shortage of organ donation is a serious social issue in Japan, various solutions to the issue have been considered. Although it was believed that the most critical factor in the organ shortage was the absence of a well-established social system, no prior studies attempted to analyz...

An increasingly unbridgeable gap exists between the supply and demand of transplantable organs. Human embryonic stem cell technology could solve the organ shortage problem by restoring diseased or damaged tissue across a range of common conditions. However, such technology faces several largely ignored immunological challenges in delivering cell lines to large populations. We address some of th...

Organ transplant has been developed in animal models over the past 100 years. The major limiting factor in transplant medicine is the shortage of donor organs. This shortage creates pressure for fair and efficient allocation of organs, with expectations that those involved in transplantation will strive to achieve optimal outcomes and ensure just access. This article reviews the major types of ...