Physical organic chemistry (POC) and reactive intermediate chemistry (RIC) belong to the core subjects of organic chemistry. During the 1990s and 2000s both had become increasingly less fashionable, and in many countries, the mass of active researchers working in POC and RIC was in danger of becoming subcritical. Consequently, in 2003, the WhitesidesReport on the status of chemistry in Great Br...

Fluorine (from "le fluor", meaning "to flow") is a second row element of Group 17 in the periodic table. When bound to carbon it forms the strongest bond in organic chemistry to give organofluorine compounds. The scientific field treating them, organofluorine chemistry, started before elemental fluorine itself was isolated. Applying the fruits in academia, industrial organofluorine chemistry ha...

introduction: glutaric academia type i is a metabolic disorder that is caused due to deficiency of glutaryl-coa dehydrogenase. macrocephaly is a common sign in ga1, although many infants usually appear healthy at birth.   case report a 5.5 year old boy with ga1was admitted to nicu. chief compliance of patient for hospitalization was pneumonia and sepsis and he was intubated and mechanically ven...

Organic anion-transporting polypeptides or OATPs are central transporters in the disposition of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of endogenous substrates. The critical role of OATPs in drug disposition has spurred research both in academia and in the pharmaceutical industry. Translational aspects with clinical questions are the focus in academia...

Supplementary Information FOR New teixobactin analogues reveal enduracididine to be non-essential for potent antibacterial activity and lipid II binding Anish Parmar, ‡ Abhishek Iyer, ‡ Stephen H. Prior, Daniel G. Lloyd, Eunice Tze Leng Goh, Charlotte S. Vincent, Timea Palmai-Pallag, Csanad Z. Bachrati, Eefjan Breukink, Annemieke Madder, Rajamani Lakshminarayanan, Edward J. Taylor and Ishwar Si...

This article examines how boundary-crossing careers influence creative knowledge combination by looking at a group of creative artists whose careers straddle professional arts and academia. Whereas previous research has treated individuals as vehicles for knowledge transmission across intertwined networks, this study emphasizes their active role as knowledge brokers. It examines how work role t...

In 2010, Richard Heck, Ei-ichi Negishi, and Akira Suzuki joined the prestigious circle of Nobel Laureate chemists for their roles in discovering and developing highly practical methodologies for C-C bond construction. From their original contributions in the early 1970s the landscape of the strategies and methods of organic synthesis irreversibly changed for the modern chemist, both in academia...

Volatile Organic Compound (VOC) measurements in the Pearl River Delta (PRD) region, China Y. Liu, M. Shao, S. H. Lu, C.-C. Chang, J.-L. Wang, and G. Chen State Joint Key Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing, China Res. Center of Environment Change, Academia Sinica, Nankang, Taipei 115, Taiwan,...

Since they were first synthesized in 1992, the ruthenium catalyst named after Nobel Laureate R. H. Grubbs have become a useful tool in organic synthesis. Compared to conventional heterogeneous metathesis catalysts, Grubbs catalysts are more reactive, faster to initiate and better for reaction control. Grubbs catalysts have been employed in good effort both in academia and industry, the later in...