methylmalonic acidemia (mma) is usually caused by a deficiency of the enzyme methylmalonyl-coa mutase (mcm), a defect in the transport or synthesis of its cofactor, adenosyl-cobalamin (cbla, cblb, cblc, cblf, cbld, and cblx), or deficiency of the enzyme methylmalonyl-coa epimerase. a comprehensive diagnostic approach involves investigations of metabolites with tandem mass spectrometry, organic ...

Complexes and clusters bridge the gap between molecular and macroscopic levels by linking individual gaseous molecules to newly formed nanoparticles but the driving forces and mechanism for the formation of complexes and clusters in the atmosphere are not well understood. We have performed ab initio and density functional quantum chemical calculations to elucidate the role of organic acids in t...

Background: Organic acids refer to a family of compounds that are intermediates in a variety of metabolic pathways. Many organic acids are present in urine from clinically normal individuals. Elevated levels of urine organic acids cause to the organic acidurias, disorders in which some metabolic pathways in organic acid metabolism are blocked. The present work identified major and minor urinary...

a study was carried out to investigate the effects of organic acid mixture as well as two methionine supplements on performance, carcass characteristics and weight of gastrointestinal tract in broiler chickens. six hundred unsexed day-old ross 308 broiler chicks were utilized in a factorial arrangement of treatments (3×2) based on completely randomized design (crd) of 4 replicates of 25 chicks ...

Background: Natural organic matters (NOMs) have the main role in formation of trihalomethanes. These compounds are in natural water sources due to biological activities. In the presented study, adsorption and separation of humic acid as an index of natural organic matters using multi-walled carbon nanotubes is evaluated. Methods: The experiments were carried out in bath adsorption reactors wit...

HE RECENT EMPHASIS on disorders of acid-base metabolism has necessitated a reappraisal of those urinary constituents which represent elimination of acid or base. The conventional expression for urinary acid excretion (“net acid excretion”) is titratable acid bicarbonate + ammonia (T.A. CO2 + NH4 ) (1). It has been the contention of this laboratory that acid excretion is more inclusively represe...