Most drugs used today are purely organic compounds. Especially after the enormous success of the cisplatin (Fig 1) in tumor treatment, interest in metal complexes has grown (Allardyce & Dyson, 2006). Synthetic organometallic compounds are generally considered to be toxic or non-compatible with biological systems. Despite this perception, the medicinal properties of organometallic compounds, in ...

Experiments exploring the potential catalytic role of iron sulfide at 250 degrees C and elevated pressures (50, 100, and 200 megapascals) revealed a facile, pressure-enhanced synthesis of organometallic phases formed through the reaction of alkyl thiols and carbon monoxide with iron sulfide. A suite of organometallic compounds were characterized with ultraviolet-visible and Raman spectroscopy. ...

Until recently, organometallic derivatives were generally viewed as moisture- and air-sensitive compounds, and consequently very challenging to synthesise and very demanding in terms of laboratory requirements (Schlenk techniques, dried solvent, glove box). However, an increasing number of stable, water-soluble organometallic compounds are now available, and organometallic chemistry in aqueous ...

The first ferrocene-fused organometallic compounds derived from the buckybowl sumanene (C21H12) are presented. Both compounds, sumanenylferrocene and 1,1'-disumanenylferrocene, have been synthesized by Negishi-type cross-coupling of iodosumanene and were studied crystallographically. Sumanenylferrocenes form unique packing motifs, which are both different from those of their corannulene congene...

In this Review we describe how the advent of machines is impacting on organic synthesis programs, with particular emphasis on the practical issues associated with the design of chemical reactors. In the rapidly changing, multivariant environment of the research laboratory, equipment needs to be modular to accommodate high and low temperatures and pressures, enzymes, multiphase systems, slurries...

1Atmospheric Environment Laboratory, Department of Environment and Energy, Sejong University, Goon Ja Dong 98, Seoul 143-747, Republic of Korea 2Palo Duro Research Center, West Texas A&M University, Canyon, TX 79016, USA 3College of Agriculture, Guangxi University, Nanning, Guangxi 530005, China 4Department of Electrical Engineering, National Tsing Hua University, No. 101, Sec. 2, Kuang-Fu Road...