OBJECTIVES Effects of acute exposure to organophosphorous pesticides (OPs), chlorphenvinphos (CVP) or chlorphyriphos (CPF) on amphetamine (AMPH)- or scopolamine (SCOP)-induced open-field locomotion were compared in rats. MATERIALS AND METHODS CVP and CPF were administered intraperitoneally, both at doses resulting in about 50% inhibition of erythrocyte acetylcholinesterase (rbcAChE). The pest...

A rapid multi-residue method was developed for the determination of 20 organophosphorous pesticide residues in leeks by gas chromatography coupled to triple quadrupole mass spectrometry (GC–QqQMS/MS). The method was based on the modified QuEChERS sample preparation method. After microwave pre-treatment, leek samples were extracted with acetonitrile containing acetic acid 0.1% and cleaned by dis...

background: the german cockroach, blattella germanica (l), is a world wide hygienic pest that is very difficult to control. extensive usage of insecticides may develop resistance to a variety of insecticides, causing failure to control. this study was designed to determine resistance of hospital-collected strains of the german cockroach to carbamate and organophosphorous insecticides. methods: ...

Aim of the study: To assess the metabolism of liver & lipid peroxidation status in the patients with organophosphorus compounds poisoning. Materials & Methods: 50 patients of both sex, age group 25 -50 years who got admitted for organophosphorous compounds poisoning in Government General Hospital Chennai-3 were chosen for the study. Age and sex matched 50 healthy volunteers were treated as cont...

Organophosphorous and organochlorine pesticides, which were banned or restricted in the US and in Europe years ago, are still applied in India to control pests affecting pulses and wheat. Their simple application, efficacy, and economic return may explain the popularity of these pesticides in Indian agriculture. Unfortunately, organophosphorous and organochlorine pesticides are in general very ...

Using molecular dynamics simulations, we modeled solvation and diffusion in aqueous solutions of organophosphorous compounds, including nerve G-agents sarin and soman (methylphosphonofluoridates) and their common simulants DMMP (dimethyl methylphosphonate) and DIFP (diisopropyl fluorophosphate). The aqueous solutions of the organophosphorous compounds were found to display complex molecular sca...

Resistance to temephos, an organophosphorous insecticide (OP), was found to be low (2-fold) in 2 Culex pipiens populations collected in Sayada (mid-eastern Tunisia). This resistance was synergized by an esterase inhibitor (DEF). Two sets of over-produced esterases (A2-B2 and A4-B4), known to be involved in resistance, were identified in almost 50% of the examined insects. In addition, 3% of ins...