نتایج جستجو برای: organoplatinum

تعداد نتایج: 68  

Journal: :Cancer 1985
M Markman B Reichman T Hakes J Curtin W Jones J L Lewis R Barakat S Rubin B Mychalczak P Saigo

During the past decade, intraperitoneal therapy of ovarian cancer has evolved from a pharmacologic model into an established treatment technique for women with this malignancy. Approximately 40% of patients with small-volume residual ovarian cancer (microscopic disease or macroscopic tumor, < or = 0.5 cm in maximum tumor diameter), after an objective response to initial organoplatinum-based sys...

Journal: :Acta crystallographica. Section C, Structural chemistry 2016
William Raven Thomas Joschko Irmgard Kalf Ulli Englert

At the molecular level, the enantiomerically pure square-planar organoplatinum complex (SP-4-4)-(R)-[2-(1-aminoethyl)-5-fluorophenyl-κ(2)C(1),N][(R)-1-(4-fluorophenyl)ethylamine-κN](isocyanato-κN)platinum(II), [Pt(C8H9FN)(NCO)(C8H10FN)], and its congener without fluorine substituents on the aryl rings adopt the same structure within error. The similarities between the compounds extend to the mo...

Journal: :iranian journal of pharmaceutical research 0
saeed irannejad department of physics, university of zanjan, zanjan, iran mohsen amini department of medicinal chemistry, faculty of pharmacy and drug design &amp; development research center, tehran university of medical sciences, tehran, iran mona modanlookordi pharmaceutical sciences research center, mazandaran university of medical sciences, sari, iran mohammad shokrzadeh department of pharmacology &amp; toxocology, pharmaceutical sciences research center, faculty of pharmacy, mazandaran university of medical sciences, sari, iran hamid irannejad department of medicinal chemistry, pharmaceutical sciences research center, faculty of pharmacy, mazandaran university of medical sciences, sari, iran

carbon nanotubes have unique properties like high stability, high surface to mass ratio and so on which make them suitable for medicinal purpose applications. treatment of cancer by organoplatinum agents like cisplatin has become unresponsive in most cases due to low distribution of drug in biological fluids, inability of drug to cross cellular membranes and low stability in biological environm...

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