The peripheral cement-ossifying fibroma is a reactive gingival overgrowth occurring mostly in the maxillary anterior region in young adults predominantly affecting women, with greater prevalence at 28 years. It originates from the cells of the periodontal ligament. The final diagnosis is established by histological examination, which reveals the presence of cellular connective tissue with focal...

Localized gingival growths are one of the maximum regularly encountered lesions within oral cavity, which taken into consideration to be reactive as opposed neoplastic. Those encompass pyogenic granuloma, inflammation fibroma, peripheral large cellular and ossifying fibroma (POF). Among those lesions, Peripheral Ossifying Fibroma (POF) is an occasionally happening non-neoplastic growth with reg...

Cemento-ossifying fibroma is a mesodermal, slow-growing, benign fibro-osseous lesion of the jaws. A case of mandibular molar enlargement that was treated previously by other surgeons and diagnosed as cemento-ossifying fibroma, is presented. Two recurrences occurred 4 and 8 years after surgery due to incomplete surgical removal.

Reactive proliferations of the gingiva comprise lesions such as pyogenic granuloma (PG), inflammatory fibroepithelial hyperplasia (IFH), peripheral ossifying fibroma (POF), and peripheral giant cell lesion. Osteopontin (OPN) has a dual role, it promotes mineralization when it is bound to solid substrate, and on the other hand, it inhibits mineralization when it is seen in association with solut...

Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma, treated wi...

Peripheral ossifying fibroma is a common solitary gingival overgrowth thought to arise from the gingival corium, periosteum or periodontal ligament. Ossifying fibroma has the propensity to occur in cranial bones, but the peripheral variety shows a close relationship with the periodontal ligament and adjacent alveolar bone. It is more commonly seen in women (predilection of 3:1) and usually at a...

Central Ossifying Fibroma in mandible: A Case Report with aggrasive behavior review of differential dragwsis

Peripheral ossifying fibroma is a benign neoplasm that usuallydevelops from gingiva, presenting as an exophytic smooth surfaced pink or red nodular mass that is sessile or is less frequently seen on a pedicle. From the Indian perspective, it is usually noticed in 5th-6th decades of life with female predilection. Microscopically, the tumour shows stratified squamous epithelium and highly cellula...

BACKGROUND The purpose of this work was to perform a systematic review regarding ossifying fibroma and its multiple variants of the paranasal sinuses, and to identify any clinical differences between the multiple variants. METHODS A search of the U.S. National Library of Medicine (PubMed) database was performed for the non–Medical Subject Heading (MeSH) search term “ossifying fibroma.” The bi...

Odontogenic fibroma (OF) is a rare benign odontogenic neoplasm that is most commonly found in the mandibular/premolar region of female patients in the second to fourth decades of life. Well-defined radiolucent lesions that may induce root resorption are normally observed. Rare variants of OF have been described in the prior literature, including references to: 1) giant cell lesions, 2) amyloid-...