Abstract Ototoxic medications can lead to significant morbidity. Thus, pre-marketing clinical trials have assessed new drugs that ototoxic potential. Nevertheless, several side effects of may remain undetected. Hence, we sought retrospectively investigate the potential risk adverse drug reactions among commonly used via a longitudinal cohort study. An electronic health records-based data analys...

Audiometric criteria establishing the ototoxic effects of cisplatin (CDDP) vary widely in the literature. Normal test-retest variability in audiometric thresholds resulting from serial audiometry is likely a confounding variable in the over-reporting of ototoxic effects. This study investigated the variability of serial audiometry for a group of 21 head and neck cancer patients receiving no kno...

INTRODUCTION High-frequency audiometry may contribute to the early detection of hearing loss caused by ototoxic medications. Many ototoxic drugs are widely used in the treatment of patients with cystic fibrosis. Early detection of hearing loss should allow known harmful drugs to be identified before the damage affects speech frequencies. The damage caused by ototoxicity is irreversible, resulti...

BACKGROUND The primary goal of chemotherapy is to cure cancer and its symptoms. Hence, in recent years, there has been an increase in cancer paediatric survival rate. However, there have also been adverse side effects such as ototoxic hearing loss because of chemotherapy. Therefore, this study aimed at exploring whether the parents of children undergoing chemotherapy are aware of ototoxic effec...

Sorry, there is no abstract. Read the first few lines of the text instead! Medicines procured from herbs, animals or the soil have been with humanity since the dawn of civilization. Mostly, we assume, as cures for our ailments, but also to our detriment, as Socrates' hemlock and Shakespeare's 'juice of cursed hebona' attest (although we might argue that the murder of Hamlet's father was not to ...

Three cases in one family are presented with oscillopsia due to vestibular areflexia, but without hearing loss. There was no history of other neurological or otological diseases (including infectious diseases) or use of neuro-ototoxic drugs. Laboratory tests, including tests for autoimmune diseases, were undisturbed. Petrosal radiographs and brain CT scans were normal. The pedigree suggested au...