1. UCL Respiratory, Royal Free Campus, University College London, London, UK, NW3 2PF Corresponding Author TEL: 020 783

PURPOSE The role of systemic inflammation on asthma-COPD overlap syndrome is unknown. This study aimed to examine systemic inflammation in asthma-COPD overlap syndrome, and to identify associations between clinical characteristics and inflammatory mediators in asthma-COPD overlap syndrome. METHODS In 108 adults older than 55 years comprising healthy controls (n=29), asthma (n=16), COPD (n=21)...

BACKGROUND/AIMS Overlap syndrome of autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) (AIH-PBC overlap syndrome) is a rare disease that has not been clearly characterized in Korean patients. This study investigated the clinical features of AIH-PBC overlap syndrome compared with those of AIH and PBC alone. METHODS This retrospective cohort study included 158 consecutive patients w...

Lichen planus (LP) and discoid lupus erythematosus (DLE) are separate disease entities. Nevertheless, patients with a so-called "overlap syndrome" have been described occasionally. The aim of the present study was to establish whether the LE/LP overlap syndrome, based on clinical and routine histological features, could be delineated from DLE or LP using immunohistochemical techniques. Formalin...

Výskyt ANCA protilátek bývá u pacientů se systémovým lupus erytematodes (SLE) popisován asi ve 24-31 % případů, nemají však vztah k distribuci a tíži orgánového postižení SLE jejich rutinní monitoring nedoporučuje. Overlap syndrom systémového s asociovanou vaskulitidou (AAV) zcela vzácně, následující kazuistika pacientky těžkým postižením ledvin v rámci AAV pou...