INTRODUCTION The aim of this study was to examine the effects of oral administration of omega-3 fatty acid on kidney functional disturbances, histological damages, and oxidative stress due to reperfusion injury. MATERIALS AND METHODS Male Sprague Dawley rats received a standard diet for 2 weeks. Through gavage, the rats in acute kidney failure and omega-3 groups received 4 mL normal saline or...

background: ionizing radiation causes deleterious effects on living system mainly due to oxidative damages of macromolecules and protein is the major target due to its abundance. the aim of this study was to investigate the effects of ionizing radiation induced changes in the molecular properties of bovine serum albumin (bsa) its secondary and tertiary structures, degradation, cross linking and...

BACKGROUND Normal erythrocyte is deformable and this facilitates blood flow in the capillaries. Oxidative stress reduces the deformability of erythrocytes, and influences on blood flow in microcirculation. The objective of this study was to investigate the deformability of erythrocytes exposed to oxidative stress, the protective effects of verapamil and ascorbic acid against oxidative damages i...

Results of the present work give evidence from the beneficial role of extra virgin olive of oil (EVOO) consumption towards oxidative stress and cardiovascular diseases. Polyphenols contained in EVOO are responsible for inhibiting lipoproteins oxidative damages and promoting reverse cholesterol transport process via ABCA1 pathway.

BACKGROUND There is an interaction between oxidative equilibrium and anti-oxidants in oxidative stress. Therefore, oxidative stress has an effect on intercellular oxidation and causes atrophy and is an underlying factor in many diseases. OBJECTIVES The aim of this study was to investigate the effect of running downhill and the short-term effect of caffeine supplementation on oxidative stress ...

diseases. These include cancer, Parkinson’s disease, Alzheimer’s disease, atherosclerosis, heart failure, myocardial infarction, Schizophrenia, bipolar disorder, fragile X syndrome, sickle cell disease and chronic fatigue syndrome. Oxidative stress is likely to be involved in agerelated development of cancer. The reactive species produced in oxidative stress can cause direct damage to the DNA a...

The oxidative damages induced by a redox imbalance cause age-related changes in cells and tissues. Superoxide dismutase (SOD) enzymes play a pivotal role in the antioxidant system and they also catalyze superoxide radicals. Since the loss of cytoplasmic SOD (SOD1) resulted in aging-like phenotypes in several types of murine tissue, SOD1 is essential for the maintenance of tissue homeostasis. Me...