in recent years, biosurfactants due to wide applications in chemical, petroleum, food andpharmaceutical industries, have been widely considered by researchers. biosurfactants are produced by aseries of microorganisms, so it is important to screen culture medium and operating conditions in miniaturized bioreactors prior to scaling up to large bioreactors.in this study, using a kind of miniaturiz...

During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we simulate blood flow and oxygen transfer in feto-placental capillaries by converting three-dimensional representations of villous and capillary surfaces, reconstructed from confocal laser scanning microscopy, to finite-element meshes, and calculating values of vascular flow res...

In this article, we propose an integrated model for oxygen transfer into the blood, coupled with a lumped mechanical model for the ventilation process. Objectives. We aim at investigating oxygen transfer into the blood at rest or exercise. The first task consists in describing nonlinear effects of the oxygen transfer under normal conditions. We also include the possible diffusion limitation in ...

in recent years, biosurfactants due to wide applications in chemical, petroleum, food andpharmaceutical industries, have been widely considered by researchers. biosurfactants are produced by aseries of microorganisms, so it is important to screen culture medium and operating conditions in miniaturized bioreactors prior to scaling up to large bioreactors.in this study, using a kind of miniaturiz...

In this research, high oxygen-barrier films were organized based on low-density polyethylene (LDPE)/ ethylene vinyl alcohol (EVOH)/ polyethylene-grafted maleic anhydride (LDPE-g-MA) compatibilizer. The effects of 10–30 wt. % EVOH and 0–10 wt. % LDPE-g-MA loadings on the properties of final films were evaluated. The morphology of specimens was observed by using scanning electron microscopy (SEM)...

Bioprocess scale-up is a fundamental component of process development in the biotechnology industry. When scaling up a mammalian cell culture process, it is important to consider factors such as mixing time, oxygen transfer, and carbon dioxide removal. In this study, cell-free mixing studies were performed in production scale 5,000-L bioreactors to evaluate scale-up issues. Using the current bi...