Under laboratory conditions, the comparative effects of two insect growth regulators, chlorfluazuron and oxymatrine, and spinosad as a biopesticide were examined on honey bee workers (Apis mellifera L.). Separate groups of bees were left for 24 h to feed on 50% sucrose solution containing different concentrations of the tested insecticides, and the lethal concentration that caused 50% mortality...

In this paper, microwave-assisted extraction (MAE) of oxymatrine from Sophora flavescens were studied by HPLC-photodiode array detection. Effects of several experimental parameters, such as concentration of extraction solvent, ratio of liquid to material, microwave power, extraction temperature, and extraction time on the extraction efficiencies of oxymatrine were evaluated. The optimal extract...

Colon cancer constitutes a major challenge all over the world, which has fourth highest incidence and third mortality rate of cancers. Although therapeutic modalities have been improved in recent years, 5 y survival remains low. Oxymatrine is one main active compounds extracted from roots Sophora flavescens was found with effect for colon Recently, microRNAs recognized as type diagnostic progno...

Mitochondrial dysfunction is the key pathogenic mechanism of cerebral injury induced by high-altitude hypoxia. Some Chinese herbal monomers may exert anti-hypoxic effects through enhancing the efficiency of oxidative phosphorylation. In this study, effects of 10 kinds of Chinese herbal monomers on mitochondrial respiration and membrane potential of cerebral mitochondria isolated from hypoxia-ex...

oxymatrine, a potent monosomic alkaloid extracted from chinese herb sophora japonica (sophora flavescens ait.). possesses anti-inflammatory activittyes.  this study was designed to investigate the effects of oxymatrine on nuclear factor–kappa b (nf-κb) and mitogen-activated protein kinase (mapk)-dependent inflammatory responses in lipopolysaccharide (lps)-activated microglia. in this paper, bv2...

Oxymatrine, a potent monosomic alkaloid extracted from Chinese herb Sophora japonica (Sophora flavescens Ait.). possesses anti-inflammatory activittyes. This study was designed to investigate the effects of oxymatrine on nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK)-dependent inflammatory responses in lipopolysaccharide (LPS)-activated microglia. In this paper, BV2 ...

Oxymatrine, a potent monosomic alkaloid extracted from Chinese herb Sophora japonica (Sophora flavescens Ait.). possesses anti-inflammatory activittyes.  This study was designed to investigate the effects of oxymatrine on nuclear factor–kappa B (NF-κB) and mitogen-activated protein kinase (MAPK)-dependent inflammatory responses in lipopolysaccharide (LPS)-activated microglia. In this paper, BV2...

The asymmetric unit of the title compound, (C(15)H(25)N(2)O(2))[FeCl(4)], contains a tetra-chloridoferrate(III) anion and a oxymatrinium cation [oxymatrine is (4R,7aS,13aR,13bR,13cS)-dodeca-hydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one 4-oxide]. The conformation of oxymatrine is similar to that of matrine with one ring having a half-chair conformation, while the others hav...

Although axonal extension to reconstruct spinal tracts should be effective for restoring function after spinal cord injury (SCI), chondroitin sulfate proteoglycan (CSPG) levels increase at spinal cord lesion sites, and inhibit axonal regrowth. In this study, we found that the water extract of roots of Sophora flavescens extended the axons of mouse cortical neurons, even on a CSPG-coated surface...

this study was conducted to investigate commercial formulations of insecticides against western flower thrips, frankliniella occidentalis (pergande).the insects were collected from commercial greenhouses of cucumber in varamin, iran. the tested insecticides were diazinon (ec 60%), cypermethrin (ec 40%), fipronil (ec 2.5%), imidacloprid (sc 35%) and a botanical insecticide oxymatrine (kingbo, as...