Here, we report the development of a new polyacrylamide (PAAm)/starch nanofibers' blend system and highlight its potential as substrate for efficient enzyme immobilization. PAAm was synthesized and blended with starch. The final blend was then electrospun into nanofibers. The response surface methodology was used to analyze the parameters that control nanofiber's diameter. Electrospun mat was t...

The hybrid hydrogel materials meet important social challenges, including the photocatalytic purification of water and bio-medical applications. Here, we demonstrate two scenarios polyacrylamide-TiO2 (PAAm@TiO2) composite design using calcium alginate (Alg-Ca) or Keplerate-type polyoxometalates (POMs) {Mo132} tuning polymer network structure. Calcium molding allowed us to produce polyacrylamide...

The purpose of the study was synthesis and physicochemical characterization spherical beads magnetically active composite ferrogels (FGs) with diameters 2–3 mm for further application to needs targeted drug delivery and/or replacement therapy. Spherical FGs based on a physical network calcium alginate (CaAlg), chemical polyacrylamide (PAAm), combined (PAAm/CaAlg) were analyzed. filled γ-Fe2O3 m...

RATIONALE Hypoplasia with an intact posterior arch of the atlas and ossification of the posterior atlantoaxial membrane (PAAM) are individually rare. PATIENT CONCERNS The patient presented with a 6-month history of progressive weakness and paresthesia of his lower extremities. DIAGNOSES Cervical myelopathy resulting from atlas hypoplasia and ossification of the posterior atlantoaxial membra...

Increased expression of matrix metalloproteinase-1 (MMP1) is associated with poor prognosis in cancers. Several single nucleotide polymorphisms (-1607GG>G, -839G>A, -755G>T, -519A>G, -422T>A, -340C>T, and 320C>T) in the MMP1 gene promoter have recently been identified. In this study, we assessed the functional effects of these polymorphisms on MMP1 gene promoter activity in cell lines of melano...

Gellan Gum (GG) was modified with N-vinyl Formamide (NVF) through PDP/Ag + redox system initiated graft copolymerization in a thermostatic water bath at 35°C under nitrogen atmosphere. The highest percentage of grafting (186%) and the lowest homopolymer content (22.2%) were achieved through a systematic optimization of the polymerization variables, including reaction time, temperature, and conc...

Single nucleotide polymorphisms (SNPs) in energy metabolism related gene may be key agents in the development of human malignancies. In this study, we aimed to examine the association of transcription factor 7-like 2, Leptin (LEP) and LEP receptor (LEPR) polymorphisms with esophageal squamous cell carcinoma (ESCC). A total of 507 ESCC cases and 1,496 controls were enrolled. We found that LEPR r...

It is now well established that many cellular functions are regulated by interactions of cells with physicochemical and mechanical cues of their extracellular matrix (ECM) environment. Eukaryotic cells constantly sense their local microenvironment through surface mechanosensors to transduce physical changes of ECM into biochemical signals, and integrate these signals to achieve specific changes...

To investigate the association of osteopontin gene -443 C>T, -156 G>GG, and -1748 A>G polymorphisms with cancer risk. The Medline, PubMed, PUBMED, EMBASE and Web of Science databases were searched. Meta-analyses were conducted using RevMan 5.2 software. After searching and evaluating the included papers, total 10 documents involved in -443 C>T, 8 papers involved in four articles involved in -15...