background: abnormal pap smear consists of premalignant or malignant cervical lesions. many of premalignant cervical lesions will never progress to invasive malignancy, or even may regress over the time. thus, there is always a risk of overtreatment of patients with an abnormal pap smear. a long-term follow-up of these patients can reveal final events associated with each  subtype of abnormal p...

BACKGROUND Severe pancreatitis is often complicated by shock and acute lung failure. Little is known about the pathophysiologic impact of the 16.6-kD lectine, named pancreatitis-associated protein (PAP), which is expressed during pancreatitis and which reduces mortality in a rat model with severe pancreatitis. Therefore, the aim of this study was to investigate the effects of PAP on the pulmona...

Di(2-ethylhexyl)phthalate (DEHP), the plasticizer used in the biomedical production of blood storage bags, hemodialysis systems, cardiopulmonary bypass (CPB) circuitry, and intubation tubes, is extracted from the plastic material when it comes into contact with biological fluids and is converted to its principal metabolite, mono(2-ethylhexyl)phthalate (MEHP). We have shown that MEHP causes card...

A bstract . This pap er concern s the study of some mathemati cal proper t ies of Thermodyn amic Au tomata . In the pr esen t pap er , t he govern ing lineari zed differenti al equat ionsfor which a rigorous trea tment is po ssibl eare studied . The driving terms are assumed period ic and t he controls are assumed piecewise const ant . T he explicit solut ion is found in the most general case w...

THE 5=-ECTONUCLEOTIDASES FOUND on the surface of most mammalian cells and in blood serum serve as a source of adenosine derived from extracellular nucleotide degradation (11). The 5=-ectonucleotidases are phosphatases whose substrate is extracellular adenosine 5=-monophosphate (AMP) generated from adenosine 5=-triand diphosphates (ATP and ADP) released from injured tissues to stimulate cellular...

Creatine plays an important role in muscle energy metabolism. Postactivation potentiation (PAP) is a phenomenon that can acutely increase muscle power, but it is an individualized process that is influenced by muscle fatigue. This study examined the effects of creatine supplementation on explosive performance and the optimal individual PAP time during a set of complex training bouts. Thirty exp...

Polyadenylation of RNA molecules in bacteria and chloroplasts has been implicated as part of the RNA degradation pathway. The polyadenylation reaction is performed in Escherichia coli mainly by the enzyme poly(A) polymerase I (PAP I). In order to understand the molecular mechanism of RNA poly-adenylation in bacteria, we characterized the biochemical properties of this reaction in vitro using th...

It has been shown recently that longterm but not short term heavy drinking of alcohol frequently results in increased serum activities of pancreatic enzymes suggesting subclinical pancreatic injury. Serum pancreatitis associated protein (PAP) is a novel protein, whose synthesis in the acinar cells and release into serum is specifically induced by acute pancreatic damage. This study was performe...

In this paper we show the rst polynomial-time algorithm for the problem of minimizing submodular functions on the product of diamonds of nite size. This submodular function minimization problem is reduced to the membership problem for an associated polyhedron, which is equivalent to the optimization problem over the polyhedron, based on the ellipsoid method. The latter optimization problem is a...

Creatine supplementation reduces the impact of muscle fatigue on post-activation potentiation (PAP) of the lower body, but its effects on the upper body remain unknown. This study examined the effects of creatine supplementation on muscle strength, explosive power, and optimal individual PAP time of the upper body during a set of complex training bouts in canoeists. Seventeen male high school c...