BACKGROUND Neurocognitive and social cognitive impairments represent important treatment targets in schizophrenia, as they are significant predictors of functional outcome. Different rehabilitative interventions have recently been developed, addressing both cognitive and psychosocial domains. Although promising, results are still heterogeneous and predictors of treatment outcome are not yet ide...

This review examines the literature on neuropsychological differences between paranoid and nonparanoid schizophrenia subjects. Thirty-two studies related to intellectual functioning, attention, memory, language, visual-spatial, and motor functions are discussed. Subjects with paranoid schizophrenia did not demonstrate higher intellectual functioning than those with nonparanoid schizophrenia, an...

OBJECTIVE Dysregulation of dopaminergic neurotransmission at the D1 receptor in the prefrontal cortex has been implicated in the pathogenesis of schizophrenia. Genetic polymorphisms of the dopamine D1-receptor gene have a plausible role in modulating the risk of schizophrenia. To determine the role of DRD1 genetic polymorphisms as a risk factor for schizophrenia, we undertook a case-control stu...

ix 1. REVIEW OF LITERATURE 1 Development of Schizophrenia as a Diagnostic Concept 1 Classifications Used in Research 3 Diagnostic Subclass 3 Paranoid Versus Non-Paranoid 3 Acute Versus Chronic 3 Process-Reactive Classification 4 Physiological Functioning in Schizophrenia ... 6 Studies of the Autonomic Nervous System . . 6 Functions Associated With the Reticular System 7 The Electroencephalogram...

Abstract Background: Lycanthropy is an unusual belief or delusion in which the patient thinks that he/she has been transformed into an animal. In rare cases, the patient believes that another person has been transformed into an animal. Case Report: We report a patient with an uncommon variant of lycanthropy is introduced. The symptoms appeared after consumption of ecstasy. This show...

The frequency and length of admissions over 50 years were analyzed in a sample of 10.268 schizophrenic patients according to ICD-10 subtypes of schizophrenia. The lowest yearly hospitalization frequencies during the risk period were observed in simple, catatonic, unspecified and hebephrenic schizophrenia. When the total sample was analyzed, unspecified schizophrenia exhibited a significantly hi...

To explore whether or not patients with schizophrenia display a more profound impairment of negative emotion processing, we assessed the implicit evaluation of positive and negative emotional stimuli. Twenty patients with schizophrenia (9 paranoid, 11 non-paranoid) and 22 normal controls were instructed to classify emotional pictures according to the intrinsic valence if the pictures were black...

There is evidence for the involvement of the endocrine system in schizophrenia. This involment was widely investigated in female patients. In the current study, we examined prolactin and estradiol serum levels in hospitalized unmedicated men with first-episode and recurrent schizophrenia and then tested possible correlation with various subtypes of the disease. In addition, the estradiol and pr...