Soft tissue is defined as the supportive tissue of various organs,the term soft tissue tumors defines neoplasms derived from soft tissue. At the clinical level, a mass is the most common sign of a soft tissue tumor. However the clinical manifestations and signs of parathyroid adenoma are not in the neck at first. Some patient who's neck was normal at physical examination. Bone pain or dysfuncti...

We present a clinical case of patient with metachronous primary multiple carcinoma left kidney (2004) adrenal metastasis (2021), occult low-grade follicular thyroid lateral neck lymph node (2019), central lung cancer (2020), hyperparathyroidism coherent parathyroid adenomas intrathyroid and typical location. Patient had undergone left-side nephrectomy bilateral adrenalectomy, double-staged thyr...

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized in man by parathyroid, pancreatic, pituitary and adrenal tumours. The MEN1 gene encodes a 610-amino acid protein (menin) which is a tumour suppressor. To investigate the in vivo role of menin, we developed a mouse model, by deleting Men1 exons 1 and 2 and investigated this for MEN1-associated tumours and ...

OBJECTIVE Angiogenic growth factors bFGF and VEGF ensure vascularisation of the growing tumor tissue. We decided to investigate their peripheral serum concentrations in patients with thyroid gland adenoma and papillary carcinoma and with parathyroid adenoma. We wanted to find the possible serum marker of these tumor diseases. METHODS 28 patients with thyroid gland tumor (14x adenoma, 14x papi...

BACKGROUND Atypical carcinoid arising from the mediastinal tissue is a rare neuroendocrine tumor and an association with parathyroid adenoma is very unusual. We report an unusual case of atypical carcinoid of mediastinum with metastasis in a patient presenting with parathyroid adenoma, which is the first case to be reported from Pakistan. CASE PRESENTATION A 51-year-old Pakistani man was seen...

Primary anterior mediastinal neoplasms comprise a diverse group of tumors and account for 50% of all mediastinal masses. Thymomas are most common and can be locally invasive and associated with parathymic syndromes. Thymic carcinomas and thymic carcinoids are rare malignancies with a propensity for local invasion and distant metastases. Thymolipomas are benign thymic tumors. The mediastinal ger...

Novel surgical applications include radioguided procedures in parathyroidectomy operations. In order to investigate the feasibility of usage of the portable gamma camera in parathyroidectomy operations; intraoperative radioguided parathyroidectomy operation was performed in three hyperparathyroidism patients with inconclusive preoperative parathyroid scintigraphy results. Intraoperative portabl...

ultrasound is one of the preferred modalities for evaluation of the parathyroid glands. this study was undertaken to determine the accuracy of high resolution ultrasound for secondary hyperparathyroidism in patients with chronic renal failure. from march 2008 to march 2009, ninety-one hemodialysis patients were examined by high resolution ultrasound (14 mhz) of the parathyroid glands in compari...