Parenteral opioid use after total knee (TKA) and hip (THA) arthroplasty often results in substantial functional interference and side effects. This prospective study compared use of traditional intravenous patient-controlled analgesia (IV PCA) with a novel oral regimen after TKA and THA. Sixty-two patients received IV PCA and 62 received scheduled long-acting and, as needed, short-acting oral o...

OBJECTIVES To conduct a systematic review for the evidence supporting or disproving the reality of parenteral nutrition- antiepileptic drugs interaction, especially with respect to the plasma protein-binding of the drug. METHODS The articles related to the topic were identified through Medline and PubMed search (1968-Feburary 2010) for English language on the interaction between parenteral nu...

INTRODUCTION Pain is a cardinal feature of inflammation and is responsible for majority of hospital visits. The non-opioid analgesics possess antipyretic and anti-inflammatory activity and thus are often employed for such purpose of controlling inflammation as well as antipyretic. The non-opioid analgesics are freely available devoid of causing dependence but their potential harmful effects can...

Breakthrough cancer pain (BTcP) has been defined as a transitory increase in pain intensity on a baseline pain of moderate intensity in patients on analgesic treatment regularly administered. This review provides updated information about the use of opioids for the treatment of BTcP, with special emphasis on the use of new rapid onset opioids (ROOs). Due to its slow onset to effect oral opioids...

The incidence of cases of malaria imported into the United Kingdom has increased.1 2 Early and appropriate treatment in Steroid-dependent patients are vulnerable to severe cases is vital, but hospital pharmacies may not always overwhelming infection with falciparum malaria stock parenteral antimalarial drugs. We report-on a case of fatal and other parasites. Parenteral antimalarial falciparum m...

A number of antipsychotic drugs have been available in the US, beginning in the early 1950s with chlorpromazine, and these drugs have proven to be immensely useful in the treatment of various psychotic illnesses, in particular schizophrenia. Several of these drugs are available in parenteral form, e.g., haloperidol and chlorpromazine, for intramuscular (IM) use. Many clinicians have found these...

A number of antipsychotic drugs have been available in the US, beginning in the early 1950s with chlorpromazine, and these drugs have proven to be immensely useful in the treatment of various psychotic illnesses, in particular schizophrenia. Several of these drugs are available in parenteral form, e.g., haloperidol and chlorpromazine, for intramuscular (IM) use. Many clinicians have found these...

The increased use of opioids in the treatment of chronic pain encourages the search for drugs with low abuse and tolerance potential but with potent analgesic activity. Opioid agonist-antagonists and partial agonists have less abuse potential than do mu opioid receptor agonists such as morphine, and have been used for many years for their analgesic affects. Recently they have been approved for ...

Analgesia with preoperative naproxen after laparoscopic sterilization was assessed in a prospective, double-blind, randomized study of 80 women; 42 women received oral naproxen 1 g, approximately 90 min before surgery, and 38 received placebo. Preoperative naproxen did not significantly influence postoperative pain scores, but was associated with a reduction in parenteral opioid administration ...

BACKGROUND There are no validated measuring tools to gauge the effectiveness of a Hospital Palliative Care Consultation Team (PCCT). One way would be to consider its effect on the consumption of opioids expressed in total amounts and different formulations administered. We perform this study to evaluate the impact of a hospital PCCT on the trends of opioid prescription in a University Hospital....