background: free radical formation and oxidative stress might play an important role in the pathogenesis of parkinson's disease (pd). in vitro data indicate that neuromelanin (nm) pigment is formed the excess cytosolic catecholamine that is not accumulated into synaptic vesicles via the vesicular monoamine transporter 2 (vmat2). we designed this study to investigate the neuroprotective eff...

antioxidants have protective effects against free radicals-induced neural damage in parkinson's disease (pd). we examined the effects of ellagic acid (ea) on locomotion, pallidal local eeg, and its frequency bands' power and also cerebral antioxidant contents in a rat model of pd induced by 6-hydroxidopamine (6-ohda). 6-ohda (16 µg/2µ l) was injected into the right medial forebrain bundle (mfb)...

the aim of this work is to use self organizing map (som) for clustering of locomotion kinetic characteristics in normal and parkinson’s disease. the classification and analysis of the kinematic characteristics of human locomotion has been greatly increased by the use of artificial neural networks in recent years. the proposed methodology aims at overcoming the constraints of traditional analysi...

background: parkinson's disease as a progressive disorder of the nervous system leads to the disability of postural control system. objectives: in the present study the effects of pilates exercises on functional balance in patients with parkinson's was investigated. materials and methods: this control trial included 30 patients with idiopathic parkinson's disease who were selecte...

INTRODUCTION This epidemiological survey estimates the hospitalization burden related to Parkinson´s Disease in Spain. METHODS This observational retrospective survey was performed by reviewing data from the National Surveillance System for Hospital Data, which includes more than 98% of Spanish hospitals. All hospitalizations of patients with Parkinson´s disease that were reported from 1997-2...

after alzheimer disease, parkinson disease (pd) is considered the most common neurodegenerative disease. its prevalence is the same in all area but it is common in males than females. from every 100 persons who are above 60 years old, one of them has pd. also 5-10% of patients are less than 40 years old. this progressive neuroinflammation disease isn’t fatal. in 60% of cases is with depression....

Background: Parkinson's disease as a progressive disorder of the nervous system leads to the disability of postural control system. Objectives: In the present study the effects of Pilates exercises on functional balance in patients with Parkinson's was investigated. Materials and Methods: This control trial included 30 patients with idiopathic Parkinson's disease who were selected as subj...

Background & Aims: This study aimed to translate Parkinson Disease Quality of Life (PDQL) Questionnaire into Persian and test its reliability and validity in Iranian patients with Parkinson disease. Method: In order to standardize the questionnaire, a standard "Forward-Backward" translation, cognitive debriefing and cultural adaptation procedure were applied and the English version of PDQL was ...