Caroline Ran, Thomas Willows, Olof Sydow, Anders Johansson, Peter Söderkvist, Nil Dizdar, Ahmad Ahmadi, Lars Olson and Carmine Belin, The HLA-DRA variation rs3129882 is not associated with Parkinsons disease in Sweden, 2013, Parkinsonism & Related Disorders, (19), 7, 701-702. http://dx.doi.org/10.1016/j.parkreldis.2013.03.001 Copyright: Elsevier. Under a Creative Commons license http://www.else...

The vision behind our project is a closed-loop system for continuous deep brain stimulation (DBS) based on features extracted from complex motion data. Our focus is on Parkinsons Disease (PD) patients, with a possible expansion to related neurological disorders. The system we envision is lightweight, will continuously gather motion information, will automatically extract high-level features fro...

parkinsonism is used to describe a syndrome manifested by any combination of six cardinal features: tremor at rest, rigidity, bradykinesia, loss of postural reflexes, flexed posture and the freezing. decreased dopaminergic neurotransmission in the basal ganglia is the core biochemical pathology in parkinsonism. hereditary parkinsonism includes various heredodegenerative diseases such as hallerv...

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Microglial activation is associated with the pathogenesis and progression of conditions such as Alzheimer's disease (AD), Parkinsons' disease, prion disease, multiple sclerosis, and ischemic and traumatic brain injury. The molecular mechanism of microglial activation is largely unknown. The expression of the purinergic, P2X7 receptor (P2X7R), is known to be enhanced in many brain pathologies wh...

BACKGROUND Epidemiological data concerning the prevalence of major depression in PD patients in Belgium is very scarce. METHODS A total of 1086 patients with idiopathic Parkinsons disease were included in the analysis. The neurological evaluation of the patients was made by the Hoehn and Yahr Staging of Parkinsons disease, the Unified Parkinson Disease Rating Scale (UPDRS), and the Schwab and...