male guinea pigs show high susceptibility to burkholderia mallei and have been used as animal models in glanders studies. the purpose of our study was to elucidate glanders comparative pathogenesis in guinea pigs. we present here the histological changes and bacterial isolation that develop over time in guinea pigs inoculated intraperitoneally (ip) with two strain of b. mallei. ten male guinea ...

the aim of this study was to assess the value of 99mtc-hexakis-2-methoxyisobutylisonitrile (mibi) scintigraphy in patients with clinical and radiologic features of primary or metastatic musculoskeletal tumors. methods: the scintigraphic findings for 84 patients were compared with the surgical and histologic findings. each patient underwent three-phase bone scan with 99mtc-methylene diphosphonat...

aim : we aimed to study the expression of cd24 and cd133 in colorectal cancer and normal adjacent tissues to assess a relationship between these markers and clinic-pathological characteristics and patient’s survival. background : cancer stem cells are a group of tumor cells that have regeneration and multi-order differentiation capabilities. patients and methods : expression of cd24 and cd133 w...

Background & Aims: Osteosarcoma is one of the most prevalent malignant bone tumors . This study is designed to assess the prognostic effect of pathologic fracture and treatment options on survival of patients with osteosarcoma. Materials & Methods: In this study, prognosis of 106 patients with limb osteosarcoma, which were treated at three  hospitals in Tehran from April to August 2012 ...

Pathologic fractures of the jaw are usually associated with aggressive, destructive lesions or malignant lesions of the jaws. Aneurysmal bone cysts (ABC) of the jaws are benign lesions which normally do not cause destruction to such an extent. This article reports a relatively aggressive ABC of the mandible in a 19 year-old male which destroyed the buccal and lingual cortices as well as th...