BACKGROUND Ginsenoside Rh2 (GRh2) is the main bioactive component in American ginseng, a commonly used herb, and its antitumor activity had been studied in previous studies. PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK), a serine/threonine protein kinase, is highly expressed in HCT116 colorectal cancer cells. METHODS We examined the effect of GRh2 on HCT116 cells ex vivo....

PURPOSE To report the results of the management of painfully symptomatic postoperative bullous keratopathy (PBK) by performing a nonpreserved human amniotic membrane (NP-AMT) transplantation in nine eyes with poor visual potential. METHODS A prospective, comparative, nonrandomized management of symptomatic PBK was done by performing a complete corneal de-epithelialization followed by a NP-AMT...

s of papers 49 and still be immunogenic. In this study, our aim is to construct a bivalent recombinant ILTV with S1 gene inserted into the TK gene region of ILTV genome, The bivalent recombinant ILTV will express S1 gene and one of the potential application is a bivalent recombinant DNA vaccine for IBV and ILTV. Firstly, TK gene and S1 gene from ILTV and IBV was isolated with PCR or RT-PCR resp...

PURPOSE To analize changing trends in indications and surgical techniques of corneal transplantation at an ophthalmological tertiary referral center in Colombia over a 7 year period. METHODS A retrospective analysis was performed of medical records from patients who underwent corneal transplantation surgeries at Fundación Oftalmológica de Santander (FOSCAL) in Bucaramanga, Colombia, between A...

BACKGROUND Recent studies have shown that the 72-kDa heat shock protein (HSP72) can be induced in renal tubular cells by a variety of stress conditions, and suggested its cytoprotective function. We have tested this hypothesis directly by transfection studies. METHODS LLC-PK1 cells (porcine renal tubular epithelial cells) were stably transfected with pBK-CMV or pBK-CMV containing the human HS...

edited by D.H. Clayton and J. Moore, Oxford University Press, 1997. pound60.00 (hbk)/ pound25.00 (pbk) (xi+473 pages) ISBN 0 19 854893 1/0 19 854892/3.

Case reporting the use of one donor cornea for two transplantation procedures: deep anterior lamellar keratoplasty (DALK) in a case of an imminent corneal perforation caused by herpetic stromal necrosis, and Descemet stripping with endothelial keratoplasty (DSEK) in an eye with pseudophakic bullous keratopathy (PBK). Descemet's membrane (DM), denuded by stromal necrosis, served as the starting ...

by Jill Lincoln, Charles H.V. Hoyle and Geoffrey Burnstock, Cambridge University Press, 1997. pound24.95 (pbk)/ pound70.00 (hbk) (xiv +363 pages) ISBN 0 521 55977 4/0 521 55038 6.

Patients with acute spinal cord injury (SCI) with paralysis experience rapid and marked muscle atrophy below the level of the lesion. Muscle is lost above the lesion due to enforced bed rest associated with immobilization. Presently, there is no viable method to quantify muscle loss between the time of injury to the initiation of rehabilitation and remobilization. Furthermore, to assess the eff...

OBJECTIVE To evaluate the clinical and histopathologic changes induced by collagen cross-linking (CXL) in pseudophakic bullous keratopathy (PBK). DESIGN Randomized, prospective, interventional study. PARTICIPANTS Twenty-four patients with PBK were included in the study. METHODS Twenty-four patients with PBK underwent CXL followed by keratoplasty at 1 or 3 months. Twelve patients underwent...